WEPX-TV (channel 38) is a television station licensed to Greenville, North Carolina, United States, broadcasting the Ion Television network to Eastern North Carolina. Owned and operated by the Ion Media subsidiary of the E. W. Scripps Company, the station maintains a transmitter northwest of New Bern, North Carolina.

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WPXU-TV (channel 35) in Jacksonville, North Carolina, operates as a full-time satellite of WEPX-TV. WPXU covers areas of southeastern North Carolina that receive a marginal to non-existent over-the-air signal from WEPX, although there is significant overlap between the two stations' contours otherwise, including in Jacksonville proper. WPXU is a straight simulcast of WEPX; on-air references to WPXU are limited to Federal Communications Commission (FCC)-mandated hourly station identifications during programming. Aside from the transmitter, WPXU does not maintain any physical presence locally in Jacksonville.

WEPX and WPXU were affiliates of MyNetworkTV from September 5, 2006, until September 27, 2009, when MyNetworkTV's affiliation switched over to WITN-TV, prior to this, the stations were solely affiliates of Ion (then known as i: Independent Television and originally known as Pax TV).

In recent years, WPXU has been carried on cable in Carolina Beach, which is within the Wilmington media market.