XAB2

XAB2
Identifiers
Aliases	XAB2, HCNP, HCRN, NTC90, SYF1, XPA binding protein 2
External IDs	OMIM: 610850 MGI: 1914689 HomoloGene: 5738 GeneCards: XAB2
Gene location (Human)
Chr.	Chromosome 19 (human)
End	7,629,545 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	3,671,316 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; canal of the cervix; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; skin of abdomen; ; body of stomach; ; gastric mucosa; ; left uterine tube; ; tibial nerve; ; popliteal artery;
	Top expressed in
	submandibular gland; ; internal carotid artery; ; external carotid artery; ; maxillary prominence; ; primitive streak; ; hair follicle; ; supraoptic nucleus; ; somite; ; ascending aorta; ; retinal pigment epithelium;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding;
Cellular component	catalytic step 2 spliceosome; membrane; nucleoplasm; spliceosomal complex; nucleus; Prp19 complex; prespliceosome; catalytic step 1 spliceosome; post-mRNA release spliceosomal complex; U2-type catalytic step 2 spliceosome;
Biological process	RNA processing; mRNA processing; transcription, DNA-templated; cellular response to DNA damage stimulus; RNA splicing; cerebral cortex development; transcription-coupled nucleotide-excision repair; blastocyst development; DNA repair; mRNA splicing, via spliceosome; generation of catalytic spliceosome for first transesterification step;
	Sources:Amigo / QuickGO
Orthologs
	56949
	67439
	ENSG00000076924
	ENSMUSG00000019470
	Q9HCS7
	Q9DCD2
	NM_020196
	NM_026156
	NP_064581
	NP_080432
	Wikidata
View/Edit Human	View/Edit Mouse

XAB2

Protein-coding gene in the species Homo sapiens

Pre-mRNA-splicing factor SYF1 is a protein that in humans is encoded by the XAB2 gene.^[5]^[6]

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This article uses material from the Wikipedia article XAB2, and is written by contributors. Text is available under a CC BY-SA 4.0 International License; additional terms may apply. Images, videos and audio are available under their respective licenses.

[refGRCh38Ensembl-1] [1]
GRCh38: Ensembl release 89: ENSG00000076924 – Ensembl, May 2017

[refGRCm38Ensembl-2] [2]
GRCm38: Ensembl release 89: ENSMUSG00000019470 – Ensembl, May 2017

[3] [3]
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] [4]
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid10944529-5] [5]
Nakatsu Y, Asahina H, Citterio E, Rademakers S, Vermeulen W, Kamiuchi S, Yeo JP, Khaw MC, Saijo M, Kodo N, Matsuda T, Hoeijmakers JH, Tanaka K (Nov 2000). "XAB2, a novel tetratricopeptide repeat protein involved in transcription-coupled DNA repair and transcription". J. Biol. Chem. 275 (45): 34931–7. doi:10.1074/jbc.M004936200. hdl:1765/3168. PMID 10944529.

[entrez-6] [6]
"Entrez Gene: XAB2 XPA binding protein 2".

[5]

[6]

[1]

[2]

[3]

[4]

XAB2

XAB2

Interactions

References

Further reading

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