The Zee Cine Award for Best Actor – Female is chosen by the viewers of Zee Entertainment Enterprises as part of its annual award ceremony for Hindi films, to recognise a female actor who has delivered an outstanding performance in a leading role. Following its inception in 1998, the ceremony was not held in 2009 and 2010, but resumed in 2011.^[1] The ceremony was again cancelled in 2021 and 2022 due to the COVID-19 Pandemic, but it resumed in 2023.

• Alia Bhatt is the most awarded actress in this category with four wins, followed by Tabu, Aishwarya Rai Bachchan, Rani Mukerji, Kajol, Vidya Balan and Deepika Padukone, who each have two wins.
• Alia Bhatt is the actress with the most consecutive wins with four, followed by Tabu, Rani Mukerji, Vidya Balan, and Deepika Padukone who each have two consecutive wins.
• Deepika Padukone is the actress with the most nominations in this category, with eleven, followed by Kajol with nine, and Kareena Kapoor Khan, Rani Mukerji, and Alia Bhatt with eight nominations each.
• The actress with the most consecutive nominations is Alia Bhatt, who received nominations for six consecutive years.
• Kajol and Deepika Padukone are the actresses who received the most nominations in a single year, with both being nominated for three films in a single year.
• Karisma Kapoor received the most nominations in this category without ever winning, with six, followed by Preity Zinta with four, and Katrina Kaif, Sonam Kapoor, Kriti Sanon, and Shraddha Kapoor with three each.
• Vidya Balan, who won the award for the second time at the age of 33, is the eldest winner, while Hema Malini became the eldest nominee at the age of 55. Kajol and Alia Bhatt are the youngest winners, having received their first awards at the age of 24, while Zaira Wasim became the youngest nominee at the age of 17.
• Vidya Balan was the first actress to win the Zee Cine Award for Best Female Debut before winning the award for Best Actress, followed by Deepika Padukone.
• Madhuri Dixit, Rani Mukerji, and Anushka Sharma are the three actresses who have won both the Best Actress and Best Supporting Actress awards.
• Aishwarya Rai Bachchan, Vidya Balan, Deepika Padukone, and Alia Bhatt are the four actresses who have won both the Best Actress and Best Actress (Critics) awards. Balan, Padukone, and Bhatt won both awards in the same year, with Balan winning for the same film and Padukone and Bhatt winning for two different films.
• Kajol and Tabu are the two actresses who have won both the Best Actress and Best Villain awards.

The following individuals have received two or more Best Actress awards:

The following individuals have received two or more Best Actress nominations, including multiple nominations in a single year.

• Zee Cine Awards
• Bollywood
• Cinema of India