Zinc finger protein 674 is a protein that in humans is encoded by the ZNF674 gene. ^[3]

Quick Facts ZNF674, Identifiers ...

ZNF674
Identifiers
Aliases	ZNF674, MRX92, ZNF673B, zinc finger protein 674
External IDs	OMIM: 300573 HomoloGene: 87837 GeneCards: ZNF674
Gene location (Human) Chr. X chromosome (human)[1] Band Xp11.3 Start 46,497,725 bp[1] End 46,545,457 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in Achilles tendon ganglionic eminence stromal cell of endometrium islet of Langerhans monocyte gallbladder gastrocnemius muscle smooth muscle tissue right lobe of liver prefrontal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function DNA binding metal ion binding nucleic acid binding DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component intracellular anatomical structure nucleus Biological process regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II negative regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 641339 n/a Ensembl ENSG00000251192 n/a UniProt Q2M3X9 n/a RefSeq (mRNA) NM_001039891 NM_001146291 NM_001190417 n/a RefSeq (protein) NP_001034980 NP_001139763 NP_001177346 n/a Location (UCSC) Chr X: 46.5 – 46.55 Mb n/a PubMed search [2] n/a
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This gene encodes a zinc finger protein with an N-terminal Kruppel-associated box-containing (KRAB) domain and 11 Kruppel-type C2H2 zinc finger domains. Like other zinc finger proteins, this gene may function as a transcription factor. This gene resides on an area of chromosome X that has been implicated in nonsyndromic X-linked mental retardation. Alternative splicing results in multiple transcript variants encoding different isoforms.