The 2020 Vanderbilt Commodores football team represented Vanderbilt University in the 2020 NCAA Division I FBS football season. The Commodores played their home games at Vanderbilt Stadium in Nashville, Tennessee, and competed in the Eastern Division of the Southeastern Conference (SEC). They were led by interim head coach Todd Fitch, who replaced Derek Mason after his firing on November 29, 2020. On December 14, 2020, Clark Lea was hired as head coach.

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2020 Vanderbilt Commodores football
Conference	Southeastern Conference
Division	Eastern Division
Record	0–9 (0–9 SEC)
Head coach	Derek Mason (7th season; first 8 games) Todd Fitch (interim; final game)
Offensive coordinator	Todd Fitch (1st season)
Offensive scheme	Multiple
Defensive coordinator	Ted Roof (1st season)
Base defense	4–3
Home stadium	Vanderbilt Stadium
Seasons ← 2019 2021 →

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On November 28, in game against Missouri, Vanderbilt's Sarah Fuller became the first woman to play in a Power Five conference game by delivering the opening kickoff for the second half. Fuller, the Commodores' goalkeeper on the school's SEC championship women's soccer team, was added to the football roster after the team's regular kicking specialists had to be quarantined due to COVID-19 protocols.^[1][2] The following game, against Tennessee in the season finale, Fuller would become the first women to score in a Power Five game, going a perfect 2/2 on extra point attempts.^[3][4]

Vanderbilt had games scheduled against Colorado State, Kansas State, Louisiana Tech and Mercer, which were all canceled due to the COVID-19 pandemic.^[6][7][8]

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Date	Time	Opponent	Site	TV	Result	Attendance
September 26	6:30 p.m.	at No. 10 Texas A&M	Kyle Field College Station, TX	SECN Alt.	L 12–17	24,073
October 3	6:30 p.m.	No. 20 LSU	Vanderbilt Stadium Nashville, TN	SECN	L 7–41	2,000
October 10	11:00 a.m.	South Carolina	Vanderbilt Stadium Nashville, TN	SECN	L 7–41	1,288
October 31	3:00 p.m.	Ole Miss	Vanderbilt Stadium Nashville, TN (rivalry)	SECN	L 21–54	840
November 7	2:30 p.m.	at Mississippi State	Davis Wade Stadium Starkville, MS	SECN	L 17–24	12,888
November 14	11:00 a.m.	at Kentucky	Kroger Field Lexington, KY (rivalry)	SECN	L 35–38	12,000
November 21	11:00 a.m.	No. 6 Florida	Vanderbilt Stadium Nashville, TN	ABC	L 17–38	1,147
November 28 [a]	11:00 a.m.	at Missouri	Faurot Field Columbia, MO	SECN	L 0–41	11,053
December 12	3:00 p.m.	Tennessee	Vanderbilt Stadium Nashville, TN (rivalry)	SECN	L 17–42	849
Homecoming Rankings from AP Poll and CFP Rankings (after November 24) released prior to game All times are in Central time

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^{^[a]} The game between Vanderbilt and Missouri was originally scheduled to take place on October 17. However, due to COVID-19 management requirements in response to positive tests and subsequent quarantine of individuals within the Vanderbilt program, the game was rescheduled for December 12.^[9][10] The SEC postponed Tennessee vs. Vanderbilt to facilitate the rescheduling of the Vanderbilt–Missouri game. The shuffling allows for the opportunity for all 14 SEC teams to play 10 regular-season games.^[11][12]