The 2021–22 season was F.C. Motagua's 75th season in existence and the club's 56th consecutive season in the top fight of Honduran football. In addition to the domestic league, the club also competed in the 2021 CONCACAF League and the 2022 CONCACAF Champions League.^[1][2]

Quick Facts season, Chairman ...

Motagua

2021–22 season
Chairman	Eduardo Atala
Managers	Diego Vásquez César Obando Hernán Medina
Stadium	Estadio Nacional
Apertura	Semifinalist
Clausura	Winners
CONCACAF League	Finalist
CONCACAF Champions League	Round of 16
Top goalscorer	League: Moreira (13) All: Moreira (17)
Home colours Away colours Third colours
← 2020–21 2022–23 →
All statistics correct as of 29 May 2022.

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Coach Diego Vásquez renewed his contract for one year and lead the team for his 16th consecutive tournament.^[3][4] Due to poor results in both domestic and international fronts, he was sacked during the Clausura tournament. He broke a league record of 350 consecutive games as manager. He was temporarily recplaced by interim coach and former star César Obando and subsequently by Argentinian manager Hernán Medina, who mnaged to win the Clausura title.^[5]

The 2021–22 home, away and third kits were published on 15 July.

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Manufacturer		Main sponsor
Joma		Pepsi
Home	Away	Alternative	Goalkeeper

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All times are local CST unless stated otherwise

Preseason and friendlies

HUEFA Soccer League v Motagua

23 July 2021 Friendly	HUEFA Soccer League	0–9	Motagua	Baton Rouge, United States
20:00			Moreira Vega Galvaliz Villafranca Klusener Bueso (o.g.) (o.g.)	Stadium: Olympia Stadium Referee: Starting XI 19 – Rougier 6 – Sánchez 7 – López 10 – Galvaliz 11 – Vega 15 – Gómez 21 – Moreira 22 – Moncada 24 – Elvir 33 – Galindo – Breyner

Florida Soccer Soldiers v Motagua

25 July 2021 Friendly	Florida Soccer Soldiers	1–4	Motagua	New Orleans, United States
19:00			Moreira Klusener Villafranca	Stadium: Pan American Stadium Referee: Starting XI 19 – Rougier 6 – Sánchez 7 – López 9 – Klusener 10 – Galvaliz 15 – Gómez 21 – Moreira 22 – Moncada 24 – Elvir 33 – Galindo – Breyner

Motagua v Olimpia

30 July 2021 Friendly	Motagua	0–0	Olimpia	Charlotte, United States
19:30 EST				Stadium: Sportsplex at Matthews Referee: Starting XI 19 – Rougier 6 – Sánchez 9 – Klusener 10 – Galvaliz 11 – Vega 12 – Santos 15 – Gómez 21 – Moreira 22 – Moncada 24 – Elvir 33 – Galindo

Motagua v Olimpia

1 August 2021 Friendly	Motagua	3–2	Olimpia	Harrison, United States
16:30 EST	Villafranca 35' Klusener 42' 48'		17' Altamirano 90' Arboleda	Stadium: Red Bull Arena Referee: Starting XI 19 – Rougier 6 – Sánchez 7 – López 9 – Klusener 10 – Galvaliz 12 – Santos 15 – Gómez 21 – Moreira 22 – Moncada 24 – Elvir 33 – Galindo

Apertura

Motagua v Platense

8 August 2021 Week 1	Motagua	3–0	Platense	Tegucigalpa
16:00	Moreira 20' Gómez 40' Martínez 70'	Report		Stadium: Estadio Nacional Referee: Jefferson Escobar Starting XI 25 – Licona 5 – Pereira 6 – Sánchez 9 – Klusener  73' 10 – Galvaliz  68' 15 – Gómez 21 – Moreira 22 – Moncada  67' 24 – Elvir 26 – Villafranca  57' 33 – Galindo Substitutes 8 – Martínez  57' 29 – Fernández  67' 23 – Delgado  68' 40 – Obando  73'
Note: Fans were allowed to access the stadium again since March 2020. Midfielder Juan Gómez scored his first goal for F.C. Motagua. Jason Sánchez and Yostin Obando made their professional debuts with the club. Obando is the son of former star César Obando.

Victoria v Motagua

11 August 2021 Week 2	Victoria	0–1	Motagua	La Ceiba
19:00		Report	36' Klusener	Stadium: Estadio Nilmo Edwards Referee: Óscar Moncada Starting XI 25 – Licona 5 – Pereira 6 – Sánchez 8 – Martínez  68' 9 – Klusener  68' 10 – Galvaliz  87' 15 – Gómez  81' 21 – Moreira 22 – Moncada  87' 24 – Elvir 33 – Galindo Substitutes 7 – López  68' 35 – Meléndez  68' 29 – Fernández  81' 23 – Delgado  87' 17 – Decas  87'
Note: This was the first encounter between these two clubs since 19 March 2016.

Marathón v Motagua

14 August 2021 Week 3	Marathón	2–0	Motagua	San Pedro Sula
15:00	Castillo 79' Costly 90'	Report		Stadium: Estadio Yankel Rosenthal Referee: Saíd Martínez Starting XI 25 – Licona 3 – Meléndez 5 – Pereira 6 – Sánchez  67'  90+5' 7 – López  64' 8 – Martínez  77' 10 – Galvaliz  77' 18 – Rodríguez 21 – Moreira  76' 29 – Fernández  76' 35 – Meléndez Substitutes 34 – López  64' 22 – Moncada  76' 26 – Villafranca  76' 23 – Delgado  77' 17 – Decas  77'
Note: Defender Carlos Meléndez made his debut with F.C. Motagua wearing the #3 jersey. Midfielder Matías Galvaliz reached 100 league appearances with the club.

Motagua v Olimpia

22 August 2021 Week 4	Motagua	3–2	Olimpia	Tegucigalpa
16:00	Pineda 8' (o.g.) Meléndez 67' Martínez 80'	Report	25' Arboleda 90+6' Hernández	Stadium: Estadio Nacional Attendance: 5,544 Referee: Selvin Brown Starting XI 19 – Rougier 5 – Pereira 10 – Galvaliz  57' 15 – Gómez  87' 21 – Moreira 22 – Moncada  46' 23 – Delgado  87' 24 – Elvir 26 – Villafranca  71' 33 – Galindo 35 – Meléndez Substitutes 29 – Fernández  46' 8 – Martínez  57' 31 – Auzqui  71' 3 – Meléndez  87' 12 – Santos  87'
Note: Argentinian midfielder Diego Auzqui made his debut for F.C. Motagua wearing the jersey #31.

Real Sociedad v Motagua

25 August 2021 Week 5	Real Sociedad	3–3	Motagua	Tocoa
19:06	Gutiérrez 9' Antúnez 44' Rocha 78'	Report	50' Klusener 74' Delgado 90+5' Villafranca	Stadium: Estadio Francisco Martínez Durón Referee: Luís Mejía Starting XI 19 – Rougier 8 – Martínez  46' 9 – Klusener  64' 12 – Santos 15 – Gómez  46' 23 – Delgado 24 – Elvir 33 – Galindo  71' 34 – López  71' 35 – Meléndez Substitutes 31 – Auzqui  46' 10 – Galvaliz  46' 26 – Villafranca  64' 29 – Fernández  71' 18 – Rodríguez  71'
Note: This became the sixth straight undefeated game at this venue.

Motagua v UPNFM

30 August 2021 Week 6	Motagua	0–0	UPNFM	Tegucigalpa
19:00		Report		Stadium: Estadio Nacional Referee: Armando Castro Starting XI 19 – Rougier 3 – Meléndez 8 – Martínez  46' 9 – Klusener  63' 17 – Decas 23 – Delgado 24 – Elvir 26 – Villafranca  46' 31 – Auzqui  54' 34 – López  63' 35 – Meléndez Substitutes 10 – Galvaliz  46' 21 – Moreira  46' 7 – López  54' 29 – Fernández  63' 11 – Vega  63'
Note: This game was pushed one day forward as the Estadio Nacional was being used as a COVID-19 vaccination site.

Honduras Progreso v Motagua

4 September 2021 Week 7	Honduras Progreso	0–3	Motagua	San Pedro Sula
19:00		Report	22' López 48' 51' Vega	Stadium: Estadio General Francisco Morazán Referee: Marvin Ortiz Starting XI 19 – Rougier 3 – Meléndez 6 – Sánchez  69' 11 – Vega  72' 17 – Decas 21 – Moreira 23 – Delgado 24 – Elvir 31 – Auzqui  57' 34 – López 35 – Meléndez  72' Substitutes 14 – Bueso  57' 10 – Galvaliz  69' 7 – López  72' 15 – Gómez  72'
Note: Youngster Geovanni Bueso made his official debut with the club wearing jersey #14.

Real España v Motagua

11 September 2021 Week 8	Real España	2–1	Motagua	San Pedro Sula
18:00	Vuelto 57' Rocca 90+4'	Report	55' Vega	Stadium: Estadio Olímpico Metropolitano Attendance: 2,000 Referee: Selvin Brown Starting XI 19 – Rougier 8 – Martínez  71' 11 – Vega  84' 17 – Decas 21 – Moreira  71' 23 – Delgado 24 – Elvir 31 – Auzqui  84' 34 – López  75' 35 – Meléndez Substitutes 9 – Klusener  71'  86'  90' 32 – Núñez  71' 7 – López  75' 4 – Mejía  84' 26 – Villafranca  84'
Note: Defender Carlos Mejía made his official debut with the club wearing jersey #4.

Motagua v Vida

16 September 2021 Week 9	Motagua	2–1	Vida	Danlí
16:00	Auzqui 19' Pereira 81'	Report	36' Tejeda	Stadium: Estadio Marcelo Tinoco Referee: Orlando Hernández Starting XI 19 – Rougier 5 – Pereira 9 – Klusener  65' 11 – Vega  65' 15 – Gómez  48' 17 – Decas 18 – Rodríguez  48' 23 – Delgado 24 – Elvir 31 – Auzqui 34 – López  74' Substitutes 35 – Meléndez  48' 8 – Martínez  48' 7 – López  65' 21 – Moreira  65' 29 – Fernández  74'
Note: Argentinian midfielder Diego Auzqui scored his first goal for F.C. Motagua.

UPNFM v Motagua

19 September 2021 Week 10	UPNFM	2–2	Motagua	Danlí
16:00	Mejía 53' Róchez 62'	Report	45' I. López 75' K. López	Stadium: Estadio Marcelo Tinoco Attendance: 1,000 Referee: Jefferson Escobar Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  65' 9 – Klusener  57' 12 – Santos  57' 14 – Bueso  57' 16 – Castellanos 18 – Rodríguez  66' 31 – Auzqui 33 – Galindo Substitutes 29 – Fernández  57' 26 – Villafranca  57' 8 – Martínez  57' 24 – Elvir  65' 34 – López  66'

Olimpia v Motagua

6 November 2021 Week 11	Olimpia	0–0	Motagua	Tegucigalpa
19:00		Report		Stadium: Estadio Nacional Referee: Melvin Matamoros Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  51' 12 – Santos 21 – Moreira  65' 23 – Delgado 24 – Elvir 34 – López  65' 35 – Meléndez  46' 54 – Hernández  46' Substitutes 31 – Auzqui  46' 18 – Rodríguez  46' 9 – Klusener  51' 22 – Moncada  65' 26 – Villafranca  65'

Motagua v Victoria

3 October 2021 Week 12	Motagua	5–0	Victoria	Tegucigalpa
16:00	López 24' 33' 71' Pereira 65' Villafranca 82'	Report		Stadium: Estadio Nacional Referee: Melvin Herrera Starting XI 19 – Rougier 5 – Pereira 7 – López  72' 11 – Vega  54' 12 – Santos 16 – Castellanos  83' 17 – Decas 18 – Rodríguez 23 – Delgado 34 – López  72' 40 – Obando  54' Substitutes 9 – Klusener  54' 59 – Oliva  54' 4 – Mejía  72' 26 – Villafranca  72' 32 – Núñez  83'
Note: Kevin López completed his first ever hat-trick with F.C. Motagua. Forward José Oliva made his debut with the club.

Platense v Motagua

9 October 2021 Week 13	Platense	2–3	Motagua	Puerto Cortés
19:00	Gutiérrez 66' (pen.) Aranda 87'	Report	2' Klusener 31' I. López 53' (pen.) K. López	Stadium: Estadio Excélsior Referee: Orlando Hernández Starting XI 19 – Rougier 7 – López  73' 9 – Klusener  73' 12 – Santos 16 – Castellanos  69' 17 – Decas 23 – Delgado  81' 24 – Elvir 31 – Auzqui  69' 34 – López 58 – Maradiaga Substitutes 22 – Moncada  69' 32 – Núñez  69' 26 – Villafranca  73' 10 – Galvaliz  73' 35 – Meléndez  81'

Motagua v Marathón

17 October 2021 Week 14	Motagua	2–1	Marathón	Tegucigalpa
16:00	Meléndez 36' López 63'	Report	69' Solano	Stadium: Estadio Nacional Referee: Jefferson Escobar Starting XI 19 – Rougier 3 – Meléndez 7 – López  78' 9 – Klusener  64' 12 – Santos 16 – Castellanos  56' 17 – Decas 23 – Delgado 24 – Elvir 31 – Auzqui  63' 34 – López  78' Substitutes 32 – Núñez  56' 10 – Galvaliz  63' 21 – Moreira  64' 29 – Fernández  78' 22 – Moncada  78'
Note: Defender Carlos Meléndez scored his first goal with the club.

Motagua v Real Sociedad

24 October 2021 Week 15	Motagua	5–1	Real Sociedad	Tegucigalpa
16:00	Meléndez 9' López 14' Mejía 67' Delgado 70' Rodríguez 86'	Report	82' Figueroa	Stadium: Estadio Nacional Referee: José Valladares Starting XI 19 – Rougier 3 – Meléndez 7 – López  46' 9 – Klusener 10 – Galvaliz  46' 17 – Decas 23 – Delgado 24 – Elvir  64' 29 – Fernández  61' 31 – Auzqui  46' 58 – Maradiaga Substitutes 11 – Vega  46' 27 – García  46' 21 – Moreira  46' 4 – Mejía  61' 18 – Rodríguez  64'
Note: Midfielder Carlos Mejía and defender Diego Rodríguez scored their first goals with F.C. Motagua.

Vida v Motagua

27 October 2021 Week 16	Vida	1–1	Motagua	La Ceiba
19:15	Palma 32'	Report	45' Klusener	Stadium: Estadio Nilmo Edwards Referee: Jefferson Escobar Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  83' 9 – Klusener  64' 17 – Decas 23 – Delgado 24 – Elvir 29 – Fernández  71' 31 – Auzqui  64' 35 – Meléndez  84' Substitutes 10 – Galvaliz  64' 11 – Vega  64' 22 – Moncada  71' 4 – Mejía  83' 6 – Sánchez  84'

Motagua v Real España

30 October 2021 Week 17	Motagua	0–1	Real España	Tegucigalpa
19:00		Report	90+5' Rocca	Stadium: Estadio Nacional Referee: Óscar Moncada Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  67' 11 – Vega  57' 17 – Decas 23 – Delgado 24 – Elvir 27 – García  46' 31 – Auzqui  57' 59 – Oliva  30' Substitutes 29 – Fernández  30' 35 – Meléndez  46' 9 – Klusener  57' 21 – Moreira  57' 4 – Mejía  67'

Motagua v Honduras Progreso

9 November 2021 Week 18	Motagua	3–2	Honduras Progreso	Tegucigalpa
19:00	Moncada 9' Moreira 21' Villafranca 59'	Report	34' (o.g.) Santos 70' Sacaza	Stadium: Estadio Nacional Referee: Saíd Martínez Starting XI 25 – Licona 10 – Galvaliz  46' 12 – Santos 15 – Gómez 16 – Castellanos 17 – Decas 21 – Moreira  59' 22 – Moncada  69' 26 – Villafranca  69' 31 – Auzqui  87' 58 – Maradiaga Substitutes 32 – Núñez  46' 29 – Fernández  59' 4 – Mejía  69' 9 – Klusener  69' 27 – García  87'
Note: F.C. Motagua finished the regular season in 4th place for the 13th time on their history.

UPNFM v Motagua

18 November 2021 Play-offs	UPNFM	1–2	Motagua	Danlí
19:05	Ramírez 90+7' (pen.)	Report	50' 57' López	Stadium: Estadio Marcelo Tinoco Referee: Nelson Salgado Starting XI 19 – Rougier 5 – Pereira 7 – López  81' 9 – Klusener  67' 12 – Santos 16 – Castellanos  87' 17 – Decas 18 – Rodríguez 23 – Delgado 31 – Auzqui  88' 34 – López  87' Substitutes 21 – Moreira  67' 11 – Vega  81' 35 – Meléndez  87' 22 – Moncada  87' 29 – Fernández  88'
Note: Forward Kevin López scored twice and reached 200 league games playing for F.C. Motagua.

Motagua v UPNFM

20 November 2021 Play-offs	Motagua	3–1	UPNFM	Tegucigalpa
18:10	López 1' Moreira 37' Villafranca 79'	Report	15' Mejía	Stadium: Estadio Nacional Referee: Luís Mejía Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  60' 12 – Santos 16 – Castellanos  64' 21 – Moreira 23 – Delgado  73' 24 – Elvir 31 – Auzqui  73' 34 – López  60' Substitutes 22 – Moncada  60' 26 – Villafranca  60' 10 – Galvaliz  64' 4 – Mejía  73' 6 – Sánchez  73'
Note: With a 5–2 win on aggregate, F.C. Motagua qualified to their 13th straight semifinal stage, and their 31st overall.

Motagua v Real España

4 December 2021 Semifnals	Motagua	1–1	Real España	Tegucigalpa
19:00	García 90+4' (o.g.)	Report	31' García	Stadium: Estadio Nacional Referee: Selvin Brown Starting XI 19 – Rougier 3 – Meléndez 5 – Pereira 7 – López  58' 9 – Klusener  46' 10 – Galvaliz  46' 12 – Santos 23 – Delgado 24 – Elvir  69' 31 – Auzqui 34 – López  58' Substitutes 26 – Villafranca  46' 21 – Moreira  46' 29 – Fernández  58' 22 – Moncada  58' 18 – Rodríguez  69'
Note: This is the fifth time in history these two sides face in a semifinal stage, having won two each in the previous four.

Real España v Motagua

11 December 2021 Semifnals	Real España	2–0	Motagua	San Pedro Sula
19:00	Rocca 61' Pereira 64' (o.g.)	Report		Stadium: Estadio General Francisco Morazán Referee: Óscar Moncada Starting XI 19 – Rougier 5 – Pereira 11 – Vega  58' 17 – Decas 18 – Rodríguez 22 – Moncada  66' 26 – Villafranca  58' 27 – García  46' 29 – Fernández  46' 32 – Núñez 35 – Meléndez Substitutes 31 – Auzqui  46' 34 – López  46' 9 – Klusener  58' 21 – Moreira  58' 7 – López  66'
Note: With a 1–3 loss on aggregate, F.C. Motagua failed in their journey to their 18th league title.

Clausura

Honduras Progreso v Motagua

19 January 2022 Week 1	Honduras Progreso	2–1	Motagua	El Progreso
19:15	Heráldez 54' Guevara 90+2'	Report	3' Moreira	Stadium: Estadio Humberto Micheletti Referee: Héctor Rodríguez Starting XI 19 – Rougier 6 – Sánchez 7 – López  64' 11 – Tejeda  64' 12 – Santos 21 – Moreira  81' 23 – Delgado 24 – Elvir 31 – Auzqui  77' 33 – Galindo 58 – Maradiaga Substitutes 18 – Rodríguez  64' 9 – Olego  64' 40 – Obando  77' 26 – Villafranca  81'
Note: A late goal on injury time, prevented F.C. Motagua to start the Clausura tournament with points. Forwards Ángel Tejeda and Franco Olego made their debuts for the club wearing jerseys 11 and 9 respectively.

Motagua v Vida

23 January 2022 Week 2	Motagua	0–0	Vida	Danlí
16:00		Report		Stadium: Estadio Marcelo Tinoco Referee: Álex Morazán Starting XI 19 – Rougier 7 – López  46' 9 – Olego  46' 11 – Tejeda  72' 12 – Santos  90+4' 17 – Decas 21 – Moreira 23 – Delgado 24 – Elvir 30 – Gonzales 31 – Auzqui  81' Substitutes 18 – Rodríguez  46' 22 – Moncada  46' 26 – Villafranca  72' 27 – García  81' 33 – Galindo  90+4'
Note: Defender Osmar Gonzales made his debut with the club with jersey #30. Still win-less as of week 2 for the first time since 2017.

Real España v Motagua

5 February 2022 Week 3	Real España	1–2	Motagua	San Pedro Sula
19:00	Denis 16'	Report	5' Meléndez 20' Tejeda	Stadium: Estadio General Francisco Morazán Referee: Óscar Moncada Starting XI 19 – Rougier 3 – Meléndez  46' 5 – Pereira 11 – Tejeda  80' 12 – Santos 17 – Decas 21 – Moreira 22 – Moncada  90+3' 31 – Auzqui  67' 32 – Núñez 34 – Baldunciel Substitutes 18 – Rodríguez  46' 24 – Elvir  67' 26 – Villafranca  80' 23 – Delgado  90+3'
Note: Argentinian midfielder Lucas Baldunciel made his debit with jersey #34. Forward Tejeda scored his first goal with F.C. Motagua.

Motagua v Victoria

8 February 2022 Week 4	Motagua	1–0	Victoria	Danlí
15:00	Olego 89'	Report		Stadium: Estadio Marcelo Tinoco Referee: Saíd Martínez Starting XI 19 – Rougier 5 – Pereira 11 – Tejeda 12 – Santos 17 – Decas  46' 21 – Moreira  59' 23 – Delgado  46' 24 – Elvir 31 – Auzqui  86' 32 – Núñez 34 – Baldunciel  68' Substitutes 18 – Rodríguez  46' 7 – López  46' 9 – Olego  59' 22 – Moncada  68' 4 – Mejía  86'
Note: Forward Franco Olego scored his first goal for the team.

Olimpia v Motagua

12 February 2022 Week 5	Olimpia	1–1	Motagua	San Pedro Sula
19:00	Velásquez 86'	Report	12' Moreira	Stadium: Estadio General Francisco Morazán Referee: Nelson Salgado Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 11 – Tejeda  84' 12 – Santos 21 – Moreira  84' 22 – Moncada  80' 23 – Delgado 24 – Elvir 32 – Núñez  70' 34 – Baldunciel  80' Substitutes 18 – Rodríguez  70' 7 – López  80' 6 – Sánchez  80' 9 – Olego  84' 26 – Villafranca  84'
Note: Goalkeeper Marlon Licona reached 100 league games with F.C. Motagua.

UPNFM v Motagua

20 February 2022 Week 6	UPNFM	0–0	Motagua	Danlí
16:00		Report		Stadium: Estadio Marcelo Tinoco Referee: Orlando Hernández Starting XI 19 – Rougier 2 – Maldonado 4 – Mejía  66' 7 – López 11 – Tejeda  62' 17 – Decas 18 – Rodríguez 22 – Moncada  46' 23 – Delgado 31 – Auzqui  60' 35 – Meléndez  46' Substitutes 9 – Olego  46' 15 – Gómez  46' 34 – Baldunciel  60' 26 – Villafranca  62' 21 – Moreira  66'

Motagua v Platense

27 February 2022 Week 7	Motagua	2–0	Platense	Tegucigalpa
16:00	Olego 23' Moreira 82'	Report		Stadium: Estadio Nacional Referee: Álex Morazán Starting XI 25 – Licona 2 – Maldonado 4 – Mejía  46' 9 – Olego  64' 11 – Tejeda  70' 12 – Santos 17 – Decas 22 – Moncada  46' 23 – Delgado  70' 32 – Núñez 35 – Meléndez Substitutes 7 – López  46' 34 – Baldunciel  46' 21 – Moreira  64' 31 – Auzqui  70' 16 – Castellanos  70'
Note: This was manager's Diego Vásquez last match leading the team. Vásquez broke a club's and league's record of 8 plus years and 350 consecutive games as coach.

Motagua v Marathón

2 March 2022 Week 8	Motagua	2–1	Marathón	Tegucigalpa
19:00	Moreira 77' (pen.) 90+3'	Report	87' Solano	Stadium: Estadio Nacional Referee: Melvin Matamoros Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López 9 – Olego  46' 12 – Santos 16 – Castellanos  57' 17 – Decas 21 – Moreira 23 – Delgado  46' 27 – García  73' Substitutes 11 – Tejeda  46' 31 – Auzqui  46' 32 – Núñez  57' 4 – Mejía  73'
Note: Former star César Obando made his professional debut as interim coach.

Real Sociedad v Motagua

6 March 2022 Week 9	Real Sociedad	2–1	Motagua	Tocoa
15:00	Martínez 58' Martínez 88'	Report	40' Decas	Stadium: Estadio Francisco Martínez Durón Referee: Selvin Brown Starting XI 19 – Rougier 2 – Maldonado 5 – Pereira 7 – López  80' 11 – Tejeda 17 – Decas 21 – Moreira  69' 23 – Delgado 32 – Núñez 35 – Meléndez  90' 40 – Obando  46' Substitutes 31 – Auzqui  46' 4 – Mejía  69' 34 – Baldunciel  80' 9 – Olego  90'
Note: Defender Wesly Decas scored his first goal for F.C. Motagua.

Motagua v Real España

13 March 2022 Week 10	Motagua	0–2	Real España	Tegucigalpa
17:00		Report	23' Chávez 53' Lacayo	Stadium: Estadio Nacional Referee: Saíd Martínez Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  68' 9 – Olego  46' 12 – Santos  46' 16 – Castellanos 17 – Decas  85' 21 – Moreira 24 – Elvir 31 – Auzqui  68' Substitutes 11 – Tejeda  46' 4 – Mejía  46' 22 – Moncada  68' 27 – García  68' 34 – Baldunciel  85'

Vida v Motagua

19 March 2022 Week 11	Vida	2–0	Motagua	La Ceiba
19:30	Agámez 38' Aguilar 66'	Report		Stadium: Estadio Nilmo Edwards Referee: Orlando Hernández Starting XI 25 – Licona 2 – Maldonado 4 – Mejía  70' 5 – Pereira 7 – López  77' 11 – Tejeda  76' 12 – Santos 16 – Castellanos  65' 23 – Delgado 24 – Elvir 34 – Baldunciel  46' Substitutes 27 – García  46' 21 – Moreira  65' 22 – Moncada  70' 40 – Obando  76' 9 – Olego  77'

Victoria v Motagua

2 April 2022 Week 12	Victoria	1–0	Motagua	La Ceiba
19:30	Lahera 41'	Report		Stadium: Estadio Nilmo Edwards Referee: Orlando Hernández Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 11 – Tejeda  86' 12 – Santos  86' 16 – Castellanos  61' 17 – Decas 21 – Moreira  70' 23 – Delgado 24 – Elvir 31 – Auzqui  70' Substitutes 7 – López  61' 9 – Olego  70' 34 – Baldunciel  70' 26 – Villafranca  86' 40 – Obando  86'
Note: New manager Hernán Medina made his debut with F.C. Motagua.

Motagua v Olimpia

6 April 2022 Week 13	Motagua	1–2	Olimpia	Tegucigalpa
19:00	Delgado 87'	Report	62' Arboleda 69' Chirinos	Stadium: Estadio Nacional Referee: Óscar Moncada Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  70' 16 – Castellanos 17 – Decas 21 – Moreira  70' 23 – Delgado 24 – Elvir  19' 31 – Auzqui  58' 35 – Meléndez Substitutes 22 – Moncada  19' 40 – Obando  58' 11 – Tejeda  70' 9 – Olego  70'
Note: F.C. Motagua lost five stright games for the first time since 2005.

Motagua v UPNFM

10 April 2022 Week 14	Motagua	2–0	UPNFM	Tegucigalpa
16:00	López 19' Meléndez 59'	Report		Stadium: Estadio Nacional Referee: Jefferson Escobar Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  80' 12 – Santos 16 – Castellanos  66' 17 – Decas 21 – Moreira  81' 22 – Moncada 34 – Baldunciel  46' 40 – Obando  66' Substitutes 35 – Meléndez  46' 4 – Mejía  66' 32 – Núñez  66' 26 – Villafranca  80' 27 – García  81'
Note: Coach Hernán Medina obtained his first victory in front of the club.

Marathón v Motagua

13 April 2022 Week 15	Marathón	0–3	Motagua	San Pedro Sula
15:06		Report	56' Moreira 84' 90+2' Mejía	Stadium: Estadio Yankel Rosenthal Referee: Armando Castro Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  86' 12 – Santos 17 – Decas 21 – Moreira  66' 22 – Moncada  73' 23 – Delgado  73' 27 – García  86' 32 – Núñez Substitutes 26 – Villafranca  66' 4 – Mejía  73' 35 – Meléndez  73' 31 – Auzqui  86' 8 – Martínez  86'
Note: This was the largest away victory against C.D. Marathón since 1978.

Motagua v Honduras Progreso

20 April 2022 Week 16	Motagua	3–2	Honduras Progreso	Tegucigalpa
17:00	Moncada 31' Martínez 66' García 76'	Report	82' Martínez 86' Martínez	Stadium: Estadio Nacional Referee: Álex Morazán Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  79' 12 – Santos 16 – Castellanos 17 – Decas 21 – Moreira  73' 22 – Moncada  60' 23 – Delgado  73' 32 – Núñez  60' Substitutes 4 – Mejía  60' 8 – Martínez  60' 11 – Tejeda  73' 27 – García  73' 9 – Olego  79'

Platense v Motagua

24 April 2022 Week 17	Platense	0–0	Motagua	Puerto Cortés
18:00		Report		Stadium: Estadio Excélsior Referee: Óscar Moncada Starting XI 25 – Licona 2 – Maldonado 4 – Mejía  76' 7 – López 12 – Santos 16 – Castellanos  62' 21 – Moreira  86' 22 – Moncada 23 – Delgado  76' 32 – Núñez 35 – Meléndez Substitutes 8 – Martínez  62' 34 – Baldunciel  76' 27 – García  76' 26 – Villafranca  86'
Note: With this scoreless draw, Platense F.C. was officially relegated to Liga de Ascenso.

Motagua v Real Sociedad

30 April 2022 Week 18	Motagua	6–0	Real Sociedad	Tegucigalpa
19:00	Gutiérrez 15' (o.g.) Maldonado 36' Moreira 55' Mejía 61' Villafranca 69' Montoya 75' (o.g.)	Report		Stadium: Estadio Nacional Referee: Armando Castro Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  67' 17 – Decas 21 – Moreira  59' 22 – Moncada  67' 23 – Delgado 31 – Auzqui  58' 32 – Núñez 35 – Meléndez  13' Substitutes 24 – Elvir  13' 4 – Mejía  58' 8 – Martínez  59' 11 – Tejeda  67' 26 – Villafranca  67'
Note: F.C. Motagua finished the regular season in 4th place. This was the fifth time in Motagua's history winning a match with a margin of six goals or more.

Vida v Motagua

4 May 2022 Play-offs	Vida	0–3	Motagua	La Ceiba
19:30		Report	50' López 73' Santos 78' Moncada	Stadium: Estadio Nilmo Edwards Referee: Álex Morazán Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López  69' 12 – Santos 16 – Castellanos  63' 17 – Decas 21 – Moreira  85' 22 – Moncada 23 – Delgado  70' 32 – Núñez  85' Substitutes 27 – García  63' 4 – Mejía  69' 8 – Martínez  70' 26 – Villafranca  85' 34 – Baldunciel  85'
Note: This is the second time in league history that these two clubs faced in this phase. Defender Raúl Santos scored his first league goal for F.C. Motagua.

Motagua v Vida

8 May 2022 Play-offs	Motagua	0–0	Vida	Tegucigalpa
17:00		Report		Stadium: Estadio Nacional Referee: Orlando Hernández Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 7 – López 12 – Santos  74' 16 – Castellanos  46' 17 – Decas 21 – Moreira  56' 22 – Moncada 23 – Delgado  46' 32 – Núñez  46' Substitutes 4 – Mejía  46' 27 – García  46' 8 – Martínez  46' 26 – Villafranca  56' 35 – Meléndez  74'
Note: With a 3–0 score on aggregate, F.C. Motagua advanced to their 14th semifinal in a row. Midfielder Héctor Castellanos reached 200 league games with the club.

Motagua v Olimpia

12 May 2022 Semifinals	Motagua	1–1	Olimpia	Tegucigalpa
19:00	Moreira 24'	Report	22' Chirinos	Stadium: Estadio Nacional Referee: Saíd Martínez Starting XI 25 – Licona 2 – Maldonado 7 – López 12 – Santos 16 – Castellanos 17 – Decas 21 – Moreira  74' 22 – Moncada 23 – Delgado  58' 32 – Núñez  85' 35 – Meléndez Substitutes 4 – Mejía  58' 26 – Villafranca  74' 27 – García  85'
Note: This is the 13th encounter between these two teams in a semifinal stage.

Olimpia v Motagua

15 May 2022 Semifinals	Olimpia	0–1	Motagua	Tegucigalpa
17:00		Report	5' Moreira	Stadium: Estadio Nacional Referee: Melvin Matamoros Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 8 – Martínez  71' 11 – Tejeda  90' 12 – Santos 17 – Decas 21 – Moreira  71' 22 – Moncada 23 – Delgado  71' 32 – Núñez  90' Substitutes 4 – Mejía  71' 26 – Villafranca  71' 27 – García  71' 3 – Meléndez  90' 6 – Sánchez  90'
Note: With a 2–1 win on aggregate, F.C. Motagua advanced to their 27th final in league's history.

Motagua v Real España

22 May 2022 Final	Motagua	3–0	Real España	Tegucigalpa
17:00	Moreira 29' Tejeda 53' López 85'	Report		Stadium: Estadio Nacional Referee: Melvin Matamoros Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 8 – Martínez  83' 11 – Tejeda 12 – Santos 17 – Decas 21 – Moreira  55' 22 – Moncada  83' 23 – Delgado  90' 32 – Núñez Substitutes 7 – López  55' 24 – Elvir  83' 27 – García  83' 16 – Castellanos  90'

Real España v Motagua

29 May 2022 Final	Real España	2–0	Motagua	San Pedro Sula
15:00	García 38' Rocca 44'	Report		Stadium: Estadio Olímpico Metropolitano Referee: Selvin Brown Starting XI 25 – Licona 2 – Maldonado 5 – Pereira 8 – Martínez  65' 11 – Tejeda  59' 12 – Santos 17 – Decas 21 – Moreira  65' 22 – Moncada  70' 23 – Delgado 32 – Núñez Substitutes 4 – Mejía  59' 16 – Castellanos  65' 26 – Villafranca  65' 24 – Elvir  70'
Note: With a 3–2 win on aggregate, F.C. Motagua obtained their 18th league title.