1960s/1970s

The Saints entered the league as an expansion franchise in the NFC West, beginning play in 1967.^[8] Their inaugural game took place against the Rams on September 17, 1967 as the Saints scored on the opening kickoff, as rookie wide-receiver John Gilliam ran the ball 94 yards for a touchdown.^[9] Despite this, the Rams defense, led by Hall of Fame linemen Deacon Jones and Merlin Olsen, crushed the Saints as they would only manage two field goals. The Rams would go onto win the game 27–13. New Orleans' first coach was former Rams Hall of Fame receiver Tom Fears, who went 0–3 vs. his former team before being fired midway through the 1970 season; ironically, his last game was a 30–17 loss to the Rams at home, a game in which the Saints blew a 14–0 lead.

The Saints would draft future pro-bowl quarterback Archie Manning second-overall in the 1971 NFL Draft, quickly becoming one of the few stars on an underwhelming team. Despite Manning's impressive play, the Rams would further torment the Saints, winning 12 of the 18 matchups against New Orleans from 1970 to 1979. Reportedly; Rams' hall-of-fame defensive end Jack Youngblood would often spare Manning from a collision after several seasons as they feared for his safety due to the poor protection from the Saints' offensive linemen.^[10][11] As a result of this, Manning often spoke with much praise for the Rams' defensemen, telling the Los Angeles Times on September 23, 1974, "The Rams front four is the best I ever faced ... I've got to say that Youngblood was nice enough to pick me up every time he knocked my ass off." During several recent interviews, Manning joked that Youngblood's career would not have been as successful without him.^[12]

1980s

Entering the 1980s, Manning and the Saints struggled further as they finished the 1980 season with a league-worst 1–15 record. Famously during a Monday Night Football game on November 24, 1980 at the Louisiana Superdome, the Rams blew out the Saints 27–7, continuing the Saints' 12-game loss streak (it reached 14 before a one-point win vs. the New York Jets). Saints broadcaster "Buddy D" Diliberto had jokingly advised Saints fans to attend the game with paper bags over their heads. Shortly afterwards; multiple fans arrived in attendance; adopting the trend, dubbing the team the "Aint's" as a humorous reaction to the team's poor play that season.^[13][14] Despite the poor 1980 campaign from the Saints, both teams would finally emerge as contenders during the decade. The San Francisco 49ers had proven to be a juggernaut of the division under Bill Walsh and Joe Montana. This left the Rams and Saints to fight for 2nd place of the division most often, the Rams stayed as a substantial competitor while the Saints had finally emerged as a contender, led by new coach Jim Mora, and their sturdy Dome Patrol defense. The Rams and Saints had finished in 2nd or 3rd in the NFC west every season from 1982 to 1989, excluding the 1985 campaign which saw the Rams top the 49ers for the division title. During the 1988 season, both teams were tied for second place after a Saints' upset victory over the Rams in Anaheim.^[15] The Saints were eager to return to the postseason following their 1987 campaign bringing the franchise to their first playoff appearance, though the strength of the defense had helped their push, the Rams stumbled following the loss to the Saints, but managed to win their final 3 consecutive games, narrowly beating out the Saints for the wild card berth. The 1989 season saw the Rams start out of the gate to a 5–1 start before they faced the Saints at home in Week 7. The Saints shockingly upset the Rams in a 40–21 blowout, the worst loss the Rams would endure that season.^[16] Despite the loss, the Rams sought vengeance when they returned to New Orleans for their Week 12 matchup on November 26. The game saw the Saints' defense take hold, as they held the Rams 17-3 going into the third quarter. The Rams' offense quickly prevailed in a potent attack as receiver Flipper Anderson finished the game with 336 yards receiving, while Jim Everett would humiliate the Saints defense, ending the game with 454 passing yards in the overtime victory, records which still stand as of 2023.^[17][18][19]

1990s

The 1990s would not fare too kindly for the Rams, poor ownership under Georgia Frontiere saw the team regress massively after their NFC Championship appearance in 1989, the 1990 season would mark the second time in 12 seasons the Saints had beaten them for the 2nd place position in the division. The Saints had also managed their first sweep of the Rams since 1987, as their once stellar offense had devolved massively. The Saints had now taken control of the series while the Rams struggled largely due to declining fan interest and budgetary issues blamed on Frontiere. The Saints would manage a six game win streak over the Rams during their final four seasons in Los Angeles before relocating to St. Louis in 1995. The Saints' playoff aspirations would also dwindle as they failed to appear in the postseason from 1993 to 1999. Despite the decline in St. Louis, the Rams quickly resurged into contention during the 1999 season under head coach Dick Vermeil and quarterback Kurt Warner. During the Week 12 matchup in St. Louis, the Rams would obliterate the Saints 43–12, eventually sweeping the Saints after being swept by New Orleans the season prior, on their way to win Super Bowl XXXIV.^[20]

2000s

The decade opened with the Rams riding high on their legendary offense dubbed The Greatest Show on Turf, despite this; their defense had fallen to the worst in the league for the 2000 season. Dick Vermeil had retired, promoting Mike Martz as head coach while the Saints hired Jim Haslett as their new head coach. Despite splitting the season matchups with the Saints, and both finishing with a 10–6 record; the Saints managed to beat out the Rams for the division title based on their divisional record. The Rams were set to face the Saints at the superdome in the 2000 NFC Wild Card game. Despite being heavy favorites to win; the Rams offense had struggled, failing to score in two consecutive quarters. Kurt Warner would turn the ball over four times as the Saints managed to edge past the Rams in the upset victory.^[21][22][23]

Despite the victory, the Saints would fall to the Vikings in the Divisional round. The Saints never managed to return to the postseason under Haslett as they declined during the middle of the decade, bottoming out during a chaotic 2005 season when they were displaced from their home by Hurricane Katrina and went 3–13. The Rams had also begun a decline as Martz' questionable leadership had begun to tear the team apart following their loss in Super Bowl XXXVI (coincidentally, in the Superdome) the season prior. The NFL had sought to realign the divisions as the introduction of the Houston Texans franchise in 2002 had warranted the creation of eight divisions across the league, relegating the Saints to the newly formed NFC South with fellow rivals the Atlanta Falcons, Carolina Panthers and Tampa Bay Buccaneers. The Rams would make their final postseason appearance in St. Louis following the 2004 season. The Saints had begun a return to form under new head coach Sean Payton and quarterback Drew Brees in 2006, hiring former Rams' assistant coach Joe Vitt in the process. Under Payton, the team managed to win Super Bowl XLIV in 2009. Meanwhile the Rams had sunken to a franchise-low 1–15 record during the 2009 season as they were shuffling coaches and enduring multiple ownership issues following the death of Georgia Frontiere in January 2008.

2010s

Entering the new decade, the Rams were deep into a rebuild while the Saints remained a formidable playoff contender under Payton. The Rams; impressed by the Saints' defense, had sought to hire Gregg Williams from New Orleans as their Defensive Coordinator in 2012. Meanwhile; the Saints were under investigation from the league after suspicion had grown over the Saints allegedly bribing players to target opponents in violent hits on-field. Less than a month after his hiring with the Rams, Williams and Payton were implicated in the New Orleans Saints bounty scandal after it was revealed the team had paid multiple defensive players to target opposing teams with the intent of injuring the opposition. As a result, Payton was suspended for the entirety of the 2012 season while Williams was suspended indefinitely and fired by the Rams on January 2, 2013.^[24][25] Despite this; former colleague Jeff Fisher sought to rehire Williams on the Rams prior to the 2014 season. The Rams had grown increasingly dissatisfied with their accommodations in St. Louis as their stadium had grown increasingly outdated and attendance had sunk to new lows, prompting owner Stan Kroenke to return the team to Los Angeles in 2016.

Prior to the 2016 season, the Rams had traded up to draft quarterback Jared Goff first overall. The Saints, holding only five picks in that year's draft; had drafted wide receiver Michael Thomas during the second round of the draft. The Rams returned to Los Angeles for the 2016 season, though Fisher's coaching staff proved unable to steer the team towards much success as they went on to finish 4–12. In the midst of the team's struggles, they endured a brutal loss to the Saints in New Orleans during week 12. Fisher had grown an increasingly strained relationship with his players, including Goff who had seen little time on-field since being drafted. Fisher finally made the decision to start Goff over Case Keenum after a terrible 4-interception game against the New York Giants in London. Spurred by his teammates, Goff managed to score his first touchdown against the Saints in only his third pass.^[26] Despite Goff's individual performance; the Saints would blow out the Rams 49–21, tying for the largest victory in the series. Payton reportedly had sought retribution against Williams for their involvement in the Bountygate scandal as multiple players reported he was cheering festively on the Saints' sideline.^[27][28][29] The Rams fired Jeff Fisher and his staff (including Williams) two weeks later, as they finished 4-12 to a rough return to Los Angeles. During the 2016 offseason, several media outlets reported that the Rams were possibly looking to hire Payton from the Saints as their new head coach.^[30][31] However; Payton declined to accept their offer as he had chosen to remain under his new five-year contract extension as head coach of the Saints, signed a year prior.^[32]

The Rams subsequently hired former Redskins' offensive coordinator Sean McVay as they continued to rebuild their coaching staff. The two teams met that season during another Week 12 matchup in Los Angeles. Rams' running back Todd Gurley had been in the midst of a potent season in which the Rams' offense lead the league (he would later win the Offensive Player of the Year award). The Saints had seen a near-equally successful campaign with rookie running back Alvin Kamara as the Saints still maintained the fifth best offense in the league that season while the Saints had been on an eight game winstreak. Quarterbacks Drew Brees and Jared Goff had nearly combined for over 600 yards that game. Kamara had emerged as a potent dual-threat back that game as he would manage six receptions and two touchdowns that game. Todd Gurley would not manage as strong of a game as Kamara though he nearly managed 80 yards rushing. The Rams managed to pull ahead in no small part thanks to their thriving offense under receivers Sammy Watkins and Robert Woods as they managed to edge past the Saints 26-20.^[33][34]

2018 NFC Championship

The two teams would finish the year with a 13-3 record as they would eventually face one another in the 2018 NFC Championship Game in New Orleans. The Rams struggled out of the gate as the Saints pulled ahead 13-10 by the half, though soon enough; the Rams' defense took hold and began minimizing the lead as the game progressed into the fourth quarter.^[44] Michael Thomas in particular had played poorly, catching 7 passes for 36 yards as he battled Peters and Aqib Talib throughout most of the game.^[45] On a critical third down play with the game tied 20-20 at the Rams' 13 yard line; Brees would throw a pass to Tommylee Lewis though the pass was incomplete as he was hit by Rams' cornerback Nickell Robey-Coleman. Payton was livid with the call as multiple fans and Saints players had noted the hit was possibly illegal as Coleman's hit came 3 seconds prior to the pass reaching his vicinity. Robey-Coleman would later express confusion after the hit as he was also expecting a penalty flag.^[46] Announcers Joe Buck and Troy Aikman were also confused as no flag was thrown by either officials following the hit.^[47] The Rams had only one timeout remaining as the Saints would have likely utilized the drive to secure the victory, however; the Saints were forced to settle for a field goal as the Rams later tied the game as it led into overtime.^[48] In overtime the Saints managed to win the coin toss as a pass interference call would also set them up on a 2nd and 16, killing their drive for a critically needed touchdown. Upon the snap; Brees was charged by Rams' linebacker Dante Fowler as he had targeted Michael Thomas to save the play, the pass was ultimately intercepted by safety John Johnson who mockingly imitated Thomas' horse-celebration in retaliation.^[49][50] Following the game, a minor scrum broke out between players angry over the call, Marcus Peters allegedly began scouring the locker rooms in search of Sean Payton. In an humorous effort to further troll the Saints in retaliation to Thomas' gesture earlier in the season, Todd Gurley posted a photoshopped picture online depicting himself in a jersey swap with referee Bill Vinovich, mocking the no-call.^[51][52] Payton later addressed reporters during the post-game press conference, furious as he expressed his anger at the call, attacking the Rams and the officiating team, "Disappointing way to lose a game...frustrating, you know. Just getting off the phone with the league office. They blew the call. We had a lot of opportunities though, but that call puts it first and ten, we only need three plays, it's a game changing call. That's where it's at".^[53][54] Thomas was equally enraged, attacking both the Rams and the officiating crew during his postgame interview.

The Rams would advance to Super Bowl LIII though they would fall to the New England Patriots 13-3. Saints fans would sign an online petition and attempt to file a lawsuit against the league for the call, but it would ultimately be dismissed.^[56]

During an interview on August 5, 2023; Jared Goff (who had been traded to Detroit prior to the 2021 season) continued to troll the Saints after being asked on his perspective of the no-call, unapologetically claiming the Saints blew their opportunity by throwing an interception once they received the ball in overtime.^[57][58][59]

2019-present

The 2019 season saw the two teams meet again in Los Angeles, though the Rams' had eagerly anticipated the matchup as the Saints had harbored much anger against them from the season prior.^{[60][61][62][63][64]} The Week 2 matchup was not without controversy as the game was tied 3–3 with 6:11 remaining in the second quarter. The Rams were at the Saints' 11 yard line. As Goff attempted a pass, Saints' defensive end Trey Hendrickson stripped the ball from his hand, which was recovered by Saints' linebacker Cameron Jordan, who returned it 87 yards for a touchdown. However, an official blew the play dead, meaning that the return and touchdown were negated even though New Orleans was allowed to retain possession.^[65] Brees suffered an injury to his hand from Rams' defensive tackle Aaron Donald and was replaced by backup Teddy Bridgewater, who struggled in relief of Brees.^[66][67] The Rams, despite struggling on offense for two and a half quarters, woke up and ran away with a 27–9 victory. Michael Thomas was particularly upset by the victory as he was seen crying on the Saints' sideline following the game.^[68] Despite the victory, the Rams struggled mightily as injuries, poor offensive line play, and overall inconsistency contributed to the team finishing 9–7 and missing the postseason. The Saints, despite losing their star quarterback for five starts, managed another 13–3 campaign but fell in an upset loss to the Minnesota Vikings in the first round of the playoffs.^[69]

Though the two teams did not play each other during the 2021 NFL season, an injury-riddled Saints team, who entered the final week of the season with an 8–8 record, needed a win against their longtime rival Atlanta Falcons and, ironically, a Rams' win against the San Francisco 49ers, to make the 2021-22 NFL playoffs. The Saints took care of their own business in Atlanta to finish the season with a 9–8 record. But the Rams, despite holding a 17-point lead on their longtime rival, could not finish the job, and the 49ers won 27–24 in overtime to clinch a playoff spot and eliminate New Orleans from playoff contention. Had the Rams defeated the 49ers, both the 49ers and Saints would have finished with 9–8 records, but the Saints would have owned the tiebreaker and made the playoffs instead of the 49ers. Instead, the 49ers finished one game better than the Saints, and the Saints barely missed the playoffs despite finishing with the same record as the 7th-seeded Philadelphia Eagles, who defeated New Orleans earlier that season and thus owned the tiebreaker for the final playoff spot.^[70] The Rams' loss to the 49ers gave the Saints and their fans even more motivation for the following season's game between the two teams.^[71] The Rams would go on to win Super Bowl LVI a month later.^[72]

The intensity between both teams had lessened in the following years, though many New Orleans fans harbor much animosity towards the Rams to this day.^[73] Following Todd Gurley's release from the Rams in 2019, it was reported that the Saints had offered to sign the running back.^[74] However; Gurley who grew up a fan of the Atlanta Falcons; rejected the Saints' offer and signed with the Falcons.^[75] The two teams were deadlocked in competition during the 2022 offseason following the Rams' victory in Super Bowl LVI, as they were both eager to sign safety Tyrann Mathieu, but he would eventually sign with the Saints despite being persuaded by Rams' cornerback Jalen Ramsey.^[76][77] The two teams met during the 2022 season, with the Saints winning as the Rams were once again plagued with roster injuries.

The two teams met again in 2023 at SoFi Stadium, marking the Saints' first regular season appearance in the Rams' new stadium.^[78][79] Both teams entered the matchup with identical 7–7 records. A win for either team in this game would have had strong playoff implications as the Rams held tiebreaker over fellow division-rival Seattle Seahawks, as the Saints did not share the same advantage over Tampa Bay who led the NFC South. The Rams won the game by a final score of 30–22, critically damaging the Saints' playoff hopes.