The Shire of Millmerran was a local government area in the Darling Downs region of Queensland, Australia, about 80 kilometres (50 mi) southwest of the regional city of Toowoomba. The shire covered an area of 4,520.8 square kilometres (1,745.5 sq mi), and existed as a local government entity from 1913 until 2008, when it amalgamated with several other councils in the Toowoomba area to become the Toowoomba Region.

The shire was located in the catchment of the Condamine and Macintyre Rivers and as well as traditional sheep and cattle grazing, industry in the shire included cotton, timber, piggeries and coal mining. The main crops grown are barley, wheat, sorghum and small grains.

The Shire of Millmerran came into existence on 24 April 1913 after its residents and those of the Pittsworth area to the northeast voted to split away from the Shire of Jondaryan.

On 15 March 2008, under the Local Government (Reform Implementation) Act 2007 passed by the Parliament of Queensland on 10 August 2007, the Shire of Millmerran merged with the City of Toowoomba and the Shires of Cambooya, Clifton, Crows Nest, Jondaryan, Pittsworth and Shire of Rosalie to form the Toowoomba Region.

The Shire of Millmerran includes the following settlements:

• Millmerran
• Bringalily
• Cecil Plains
• Domville
• Lavelle
• Lemontree
• Pampas
• Tummaville
• Turallin
• Yandilla

• 1925: J. McKenzie ^[2]
• 1927: J. McKenzie ^[3]
• 2004—2008: Paul Antonio