GPR52

GPR52

GPR52

Protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.[5][6]

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Members of the G protein-coupled receptor (GPR) family play important roles in signal transduction from the external environment to the inside of the cell.[supplied by OMIM][6]

Cannabidiol, CBD, and O-1918 are Inverse agonist at GPR52[7]

References

  1. [1]
    GRCh38: Ensembl release 89: ENSG00000203737 – Ensembl, May 2017
  2. [2]
    GRCm38: Ensembl release 89: ENSMUSG00000118401 – Ensembl, May 2017
  3. [3]
    "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. [4]
    "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. [5]
    Sawzdargo M, Nguyen T, Lee DK, Lynch KR, Cheng R, Heng HH, George SR, O'Dowd BF (Mar 1999). "Identification and cloning of three novel human G protein-coupled receptor genes GPR52, PsiGPR53 and GPR55: GPR55 is extensively expressed in human brain". Brain Res Mol Brain Res. 64 (2): 193–8. doi:10.1016/S0169-328X(98)00277-0. PMID 9931487.
  6. [6]
    "Entrez Gene: GPR52 G protein-coupled receptor 52".
  7. [7]
    Stott LA, Brighton CA, Brown J, Mould R, Bennett KA, Newman R, Currinn H, Autore F, Higueruelo AP, Tehan BG, MacSweeney C (2021-06-01). "Characterisation of inverse agonism of the orphan-G protein-coupled receptor GPR52 by cannabinoid ligands Cannabidiol and O-1918". Heliyon. 7 (6): e07201. Bibcode:2021Heliy...707201S. doi:10.1016/j.heliyon.2021.e07201. ISSN 2405-8440. PMC 8219759. PMID 34189291.

Further reading

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