The New York City Landmarks Preservation Commission (LPC), formed in 1965, is the New York City governmental commission that administers the city's Landmarks Preservation Law. Since its founding, it has designated over a thousand landmarks, classified into four categories: individual landmarks, interior landmarks, scenic landmarks, and historic districts.

The New York City borough of Manhattan contains a high concentration of designated landmarks, interior landmarks and historic districts. The section of Manhattan between 14th Street and 59th Street includes Midtown Manhattan and other neighborhoods, and includes numerous individual landmarks, interior landmarks, and historic districts, as well as two scenic landmarks. The following is an incomplete list. Some of these are also National Historic Landmark (NHL) sites, and NHL status is noted where known.

source: ; ; date listed is date of designation;

This list is incomplete; you can help by adding missing items. (August 2008)

• List of New York City Designated Landmarks in Manhattan below 14th Street
• List of New York City Designated Landmarks in Manhattan from 59th to 110th Streets
• List of New York City Designated Landmarks in Manhattan above 110th Street
• National Register of Historic Places listings in New York County, New York
• List of National Historic Landmarks in New York City

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