Computational method for screening drug compounds can help predict which ones will work best against tuberculosis or other diseases.
Oct. 15, 2020 • ~7 min
machine-learning mathematics medicine drug-discovery artificial-intelligence broad-institute research school-of-engineering school-of-science electrical-engineering-computer-science-eecs computer-science-and-artificial-intelligence-laboratory-csail biological-engineering mit-schwarzman-college-of-computing
Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.
Oct. 13, 2020 • ~7 min
chemistry broad-institute ragon-institute research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes
The TestBoston study will facilitate at-home testing on 10,000 people for both the SARS-CoV-2 virus and antibodies against it to increase access to testing and surveillance.
Oct. 6, 2020 • ~5 min
covid-19 health-medicine brigham-and-womens-hospital broad-institute sars-cov-2 covid-tests testboston
A CRISPR-based test developed at MIT and the Broad Institute can detect nearly as many cases as the standard Covid-19 diagnostic.
Sept. 17, 2020 • ~5 min
medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute
New analysis could help uncover potential drug targets for attention deficits and sensory hypersensitivity.
July 22, 2020 • ~7 min
neuroscience mental-health autism broad-institute research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute
Unique survey of gene expression by cell type in humans and mice reveals several deficits affecting the most vulnerable neurons.
July 21, 2020 • ~7 min
neuroscience rna immunology broad-institute research cells school-of-science brain-and-cognitive-sciences computer-science-and-artificial-intelligence-laboratory-csail picower-institute huntingtons
Seven researchers discuss the importance of COVID-19 research and pandemic preparedness, the value of teamwork, and the fragility of life.
July 17, 2020 • ~17 min
covid-19 coronavirus pandemic health-medicine broad-institute anna-greka benjamin-gewurz deb-hung marcia-goldberg michael-gillette pradeep-natarajan roby-bhattacharyya
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
June 29, 2020 • ~7 min
covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute
Researchers discover mysterious bacteria that break it down in the gut.
June 24, 2020 • ~6 min
science-technology chemistry heart-disease bacteria emily-balskus chemistry-and-chemical-biology broad-institute caitlin-mcdermott-murphy microbiome microbes gut microbiology ramnik-xavier center-for-microbiome-informatics-and-therapeutics cholesterol cell-host-and-microbe coprostanol damian-plichta douglas-kenny metagenomics
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.
June 8, 2020 • ~4 min
neuroscience immunology broad-institute disease research school-of-science brain-and-cognitive-sciences picower-institute