Engineers use “DNA origami” to identify vaccine design rules
In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.
Tags: covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute
The connection between microbes and cholesterol levels
Researchers discover mysterious bacteria that break it down in the gut.
Tags: science-technology chemistry heart-disease bacteria emily-balskus chemistry-and-chemical-biology broad-institute caitlin-mcdermott-murphy microbiome microbes gut microbiology ramnik-xavier center-for-microbiome-informatics-and-therapeutics cholesterol cell-host-and-microbe coprostanol damian-plichta douglas-kenny metagenomics
Research highlights immune molecule’s complex role in Huntington’s disease
Knocking out the immune cytokine IL-6 exacerbates symptoms in HD model mice, affects neural connection genes.
Tags: neuroscience immunology broad-institute disease research school-of-science brain-and-cognitive-sciences picower-institute
Gene editing may be a path to restore partial hearing
Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.
Tags: science-technology dna chemistry crispr genome basic-research howard-hughes-medical-institute chemistry-and-chemical-biology rna gene-editing broad-institute caitlin-mcdermott-murphy deafness hearing-loss cas9 base-editing base-editors david-liu genetic-disease genetic-engineering sickle-cell-anemia progeria tmc1
Synthetic microbial system developed to find objects’ origin
DNA-barcoded microbial spores can trace origin of objects, agricultural products.
Tags: science-technology basic-research broad-institute sherlock probiotic dna-barcodes dna-barcoded-microbial-system foodborne-illnesses
Scientists find a new way to reverse symptoms of Fragile X
Drug compound, tested in mice, could be effective in treating the leading heritable cause of intellectual disability and autism.
Tags: medicine autism broad-institute research school-of-science brain-and-cognitive-sciences picower-institute
A connection between ancestry and the molecular makeup of cancer
A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.
Tags: cancer basic-research health-medicine tumors broad-institute human-genome-project ancestry nci-cancer-genome-analysis-network
SHERLOCK-based one-step test provides rapid and sensitive Covid-19 detection
New CRISPR-based research tool delivers results in an hour; researchers share protocol and kits to advance research and move toward clinical validation.
Tags: dna medicine crispr public-health covid-19 pandemic broad-institute viruses research school-of-science brain-and-cognitive-sciences health-science-and-technology
New technology could provide rapid detection of COVID-19
The CRISPR-based molecular diagnostics chip’s capacity ranges from detecting a single type of virus in more than 1,000 samples at a time to searching a small number of samples for more than 160 different viruses, including the COVID-19 virus.
Tags: science-technology engineering covid-19 basic-research broad-institute carmen combinatorial-arrayed-reactions-for-multiplexed-evaluation-of-nucleic-acids crispr-based
Researchers identify cells likely targeted by Covid-19 virus
Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.
Tags: chemistry covid-19 broad-institute ragon-institute disease viruses research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes
Page 1 of 9