Enzymes are the engines of life − machine learning tools could help scientists design new ones to tackle disease and climate change

Enzymes significantly speed up the chemical reactions that keep you alive. Researchers are using AI to create new ones to tackle modern challenges.

Sam Pellock, Postdoctoral Scholar in Biochemistry, University of Washington • conversation
Feb. 13, 2025 ~9 min

Microbes can colonize space, produce drugs and create energy − researchers are simulating their inner workings to harness how

Using digital blueprints of the metabolism of microbes, scientists can simulate expensive and time-intensive experiments set in space, power plants and farm fields.

Blaise Manga Enuh, Postdoctoral Research Associate in Microbial Genomics and Systems Biology, University of Wisconsin-Madison • conversation
Jan. 6, 2025 ~8 min


Study across multiple brain regions discerns Alzheimer’s vulnerability and resilience factors

Genomics and lab studies reveal numerous findings, including a key role for Reelin amid neuronal vulnerability, and for choline and antioxidants in sustaining cognition.

David Orenstein | The Picower Institute for Learning and Memory • mit
July 24, 2024 ~11 min

Viruses are doing mysterious things everywhere – AI can help researchers understand what they’re up to in the oceans and in your gut

Scientists are discovering viral genetic sequences in the wild faster than they can analyze them. A kind of ChatGPT for proteins can help make sense of all that data.

Libusha Kelly, Associate Professor of Systems and Computational Biology, Microbiology and Immunology, Albert Einstein College of Medicine • conversation
May 15, 2024 ~7 min

Search algorithm reveals nearly 200 new kinds of CRISPR systems

By analyzing bacterial data, researchers have discovered thousands of rare new CRISPR systems that have a range of functions and could enable gene editing, diagnostics, and more.

Allessandra DiCorato | Broad Institute • mit
Nov. 23, 2023 ~8 min

Making genetic prediction models more inclusive

MIT computer scientists developed a way to calculate polygenic scores that makes them more accurate for people across diverse ancestries.

Anne Trafton | MIT News • mit
Oct. 26, 2023 ~9 min

Cracking the code that relates brain and behavior in a simple animal

MIT researchers model and create an atlas for how neurons of the worm C. elegans encode its behaviors, make findings available on their “WormWideWeb.”

David Orenstein | The Picower Institute for Learning and Memory • mit
Aug. 23, 2023 ~9 min

Cancer evolution is mathematical – how random processes and epigenetics can explain why tumor cells shape-shift, metastasize and resist treatments

An epigenetic model of cancer that incorporates the concept of stochasticity could also explain why cancer risk increases with age and how biological development can be reversible.

Andrew Feinberg, Professor of Biomedical Engineering, Johns Hopkins University • conversation
Feb. 10, 2023 ~8 min


An interdisciplinary journey through living machines

With NEET, Sherry Nyeo is discovering MIT’s undergraduate research community at the intersection of computer science and biological engineering.

Jiyoo Jye | New Engineering Education Transformation (NEET) program • mit
Oct. 18, 2022 ~5 min

New CRISPR-based map ties every human gene to its function

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

Eva Frederick | Whitehead Institute • mit
June 9, 2022 ~9 min

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