Did He Jiankui 'Make People Better'? Documentary spurs a new look at the case of the first gene-edited babies

Scientific and public uproar resulted when the Chinese scientist announced the births of the first human babies with heritable edits to their genes. A new documentary reexamines the saga.

G. Owen Schaefer, Assistant Professor in Biomedical Ethics, National University of Singapore • conversation
Dec. 20, 2022 ~11 min

New CRISPR-based tool inserts large DNA sequences at desired sites in cells

Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.

Anne Trafton | MIT News Office • mit
Nov. 24, 2022 ~8 min


Scientists unveil the functional landscape of essential genes

Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.

Nicole Davis | Whitehead Institute • mit
Nov. 21, 2022 ~6 min

A new control system for synthetic genes

Researchers have developed a technique that could help fine-tune the production of monoclonal antibodies and other useful proteins.

Anne Trafton | MIT News Office • mit
Nov. 1, 2022 ~7 min

A “door” into the mitochondrial membrane

Study finds the protein MTCH2 is responsible for shuttling various other proteins into the membrane of mitochondria. The finding could have implications for cancer treatments and MTCH2-linked conditions.

Eva Frederick | Whitehead Institute • mit
Oct. 25, 2022 ~7 min

Y chromosome loss through aging can lead to an increased risk of heart failure and death from cardiovascular disease, new research finds

The negative health effects of Y chromosome loss could be one potential reason women tend to live longer than men.

Kenneth Walsh, Professor of Internal Medicine, University of Virginia • conversation
July 14, 2022 ~5 min

New CRISPR-based map ties every human gene to its function

Jonathan Weissman and collaborators used their single-cell sequencing tool Perturb-seq on every expressed gene in the human genome, linking each to its job in the cell.

Eva Frederick | Whitehead Institute • mit
June 9, 2022 ~9 min

'Jurassic World' scientists still haven't learned that just because you can doesn't mean you should – real-world genetic engineers can learn from the cautionary tale

As genetic engineering and DNA manipulation tools like CRISPR continue to advance, the distinction between what science ‘could’ and ‘should’ do becomes murkier.

Andrew Maynard, Professor of Responsible Innovation, Arizona State University • conversation
June 9, 2022 ~11 min


Convenience-sized RNA editing

MIT neuroscientists expand CRISPR toolkit with new, compact Cas7-11 enzyme.

Sarah CP Williams | McGovern Institute for Brain Research • mit
May 31, 2022 ~6 min

New research center focused on brain-body relationship established at MIT

K. Lisa Yang Brain-Body Center to investigate the brain’s complex relationship with other body systems.

Julie Pryor | McGovern Institute for Brain Research • mit
May 25, 2022 ~6 min

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