The world's southernmost tree hangs on in one of the windiest places on Earth – but climate change is shifting those winds

A team of researchers found the southernmost tree and forest on Earth at the extreme tip of South America. Wind limits where trees grow on Isla Hornos and those wind patterns are shifting.

Brian Buma, Assistant Professor of Integrative Biology, University of Colorado Denver • conversation
Sept. 30, 2020 ~6 min

climate-change south-america trees wind discovery exploration

To be a great innovator, learn to embrace and thrive in uncertainty

Many great innovators have personality traits in common. Comfort with uncertainty is critical, but passion, curiosity and a number of other learnable skills can prime you for an innovate idea.

Todd Saxton, Associate Professor of Strategy and Entrepreneurship, Indiana University • conversation
Sept. 15, 2020 ~8 min

innovation business risk uncertainty invention entrepreneurship disney innovation-and-invention discovery success disruption process-of-innovation

Cell ‘membrane on a chip’ could speed up screening of drug candidates for COVID-19

Researchers have developed a human cell ‘membrane on a chip’ that allows continuous monitoring of how drugs and infectious agents interact with our cells, and

Cambridge University News • cambridge
July 6, 2020 ~6 min

advanced-materials drug-discovery covid-19 coronavirus

Scientists tap the world's most powerful computers in the race to understand and stop the coronavirus

Scanning through billions of chemicals to find a few potential drugs for treating COVID-19 requires computers that harness together thousands of processors.

Jeremy Smith, Governor's Chair, Biophysics, University of Tennessee • conversation
June 3, 2020 ~9 min

medicine drug-discovery covid-19 coronavirus pandemic molecular-biology antiviral-drugs viruses computational-biology proteins sars-cov2 biophysics drug supercomputers

How Europe's CHEOPS satellite will improve the hunt for exoplanets

The primary objective of CHEOPS is to better understand the planets that we’ve already found. And its mission is now in full swing.

Jason Steffen, Assistant Professor of Physics and Astronomy, University of Nevada, Las Vegas • conversation
May 27, 2020 ~6 min

 space  astronomy  exoplanets  kepler-mission  planet  exoplanet-discovery  tess

We found and tested 47 old drugs that might treat the coronavirus: Results show promising leads and a whole new way to fight COVID-19

Researchers at the University of California, San Francisco, identified nine existing drugs that show promise to treat COVID-19. The proteins they target haven't been tried before.

Nevan Krogan, Professor and Director of Quantitative Biosciences Institute & Senior Investigator at the Gladstone Institutes, University of California, San Francisco • conversation
April 30, 2020 ~10 min

drugs health drug-discovery covid-19 coronavirus rna fda sars-cov-2 viruses hydroxychloroquine cells progesterone treatments anti-virals

COVID-19 treatment might already exist in old drugs – we're using pieces of the coronavirus itself to find them

Among the more than 20,000 drugs approved by the FDA, there may be some that can treat COVID-19. A team at the University of California, San Francisco, is identifying possible candidates.

Nevan Krogan, Professor and Director of Quantitative Biosciences Institute, University of California, San Francisco • conversation
March 20, 2020 ~8 min

 drugs  drug-discovery  covid-19  coronavirus  fda  sars-cov-2  treatment  disease  antiviral-drugs  viruses  viral-infections  drug-research

Deep learning AI discovers surprising new antibiotics

Pathogens rapidly evolve resistance to antibiotics. AI could keep us a step ahead of deadly infections.

Sriram Chandrasekaran, Assistant Professor of Biomedical Engineering, University of Michigan • conversation
Feb. 20, 2020 ~7 min

 drug-discovery  artificial-intelligence  deep-learning  antibiotic-resistance  antibiotics  drug-resistance  tuberculosis  e-coli

Whitehead Institute team resolves structure of master growth regulator

New research reveals how mTORC1 docks at lysosomal surface.

Nicole Davis | Whitehead Institute • mit
Oct. 18, 2019 ~6 min

drug-discovery biology research school-of-science national-institutes-of-health-nih whitehead-institute