How spit gets its ‘army’ of proteins

A new paper maps out how saliva gets its many proteins. It's a baseline for further investigations into spit as diagnostic fluid.

Charlotte Hsu-Buffalo • futurity
Nov. 20, 2020 ~6 min

enzymes proteins health-and-medicine mouth saliva

Tweaked enzyme may treat spine injury and stroke damage

An enzyme called chondroitinase ABC that regrows damaged nerve tissue in animals has been too unstable for human use. New work could change things.

Jim Barlow-Oregon • futurity
Sept. 8, 2020 ~6 min

stroke neurons enzymes health-and-medicine traumatic-injury spinal-cord

Tuning PARP inhibitor drug amps up its cancer-killing power

With modification a PARP inhibitor drug that's struggled in clinical trials kills cancer much more effectively, researchers say.

Melissa Moody-Penn • futurity
April 10, 2020 ~5 min

dna cancer enzymes health-and-medicine medications

1 enzyme is key for successful fertilization

One enzyme may determine whether human development starts correctly. The discovery could help explain why some fertilization fails.

Mathias Traczyk-Copenhagen • futurity
April 3, 2020 ~3 min

genes enzymes eggs fetus health-and-medicine sperm fertilization

Method reprograms cells to build stuff on brain cells

A new technique called genetically targeted chemical assembly reprograms cells to build artificial structures to carry out functions inside the body.

Stanford • futurity
March 23, 2020 ~4 min

autism neurons brains enzymes epilepsy health-and-medicine

New class of enzymes could lead to bespoke diets, therapeutics

Professor Emily Balskus and her team have identified an entirely new class of enzymes that degrade chemicals essential for neurological health, but also help digest foods like nuts, berries, and tea, releasing nutrients that may impact human health.

Caitlin McDermott-Murphy • harvard
Feb. 18, 2020 ~6 min

 science-technology  chemistry  diet  cancer  bacteria  parkinsons-disease  basic-research  emily-balskus  chemistry-and-chemical-biology  science  caitlin-mcdermott-murphy  microbiome  vayu-maini-rekdal  microbes  berries  bespoke-diets  chocolate  coffee  dopamine  enzymes  gut  l-dopa  microbiology  nutrition  nuts

Filaments are weapons in ‘world’s oldest war’

New research shows how a once-forgotten cellular structure fights in the "world’s oldest war," the battle between bacteria and viruses.

Mikayla Mace-Arizona • futurity
Dec. 4, 2019 ~5 min

dna bacteria enzymes viruses cells science-and-technology

Researchers can program a CRISPR enzyme to kill viruses in human cells

Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Karen Zusi • harvard
Oct. 10, 2019 ~5 min

 science-technology  crispr  ebola  rna  virus  broad-institute-of-mit-and-harvard  carver  cas13-enzyme  cas13-assisted-restriction-of-viral-expression-and-readout  flu  rna-based-viruses  sherlock  zika

Next antibiotic may come from dirt bacteria

"...we really need new structural classes of antibiotics that have never been contaminated by clinical resistance from established antibiotic classes."

Talia Ogliore-WUSTL • futurity
Aug. 2, 2019 ~7 min

bacteria soil antibiotics drug-resistance enzymes drug-development featured health-and-medicine

Enzyme in blood of young mice slows aging in older ones

"We were surprised by the dramatic differences between the old mice that received the eNAMPT of young mice and old mice that received saline as a control."

Julia Evangelou Strait-WUSTL • futurity
June 17, 2019 ~6 min

aging enzymes blood featured health-and-medicine lifespan

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