Immune health is all about balance – an immunologist explains why both too strong and too weak an immune response can lead to illness

Dietary supplements claim to be able to ‘boost your immune system’ to combat disease. But attaining immune balance through a healthy lifestyle and vaccination is a safer bet to keep in good health.

Aimee Pugh Bernard, Assistant Professor of Immunology and Microbiology, University of Colorado Anschutz Medical Campus • conversation
Nov. 20, 2023 ~6 min

New study explains how exercise reduces chronic inflammation

Research in mice shows that exercise mobilizes inflammation-countering T cells, lowering levels of interferon — a key driver of chronic inflammation, inflammatory diseases, and aging.

Ekaterina Pesheva • harvard
Nov. 3, 2023 ~8 min


Immune cells that fight cancer become exhausted within hours of first encountering tumors – new research

T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.

Michael Rudloff, MD-Ph.D. Candidate in Molecular Pathology and Immunology, Vanderbilt University • conversation
Aug. 3, 2023 ~6 min

Immune cells in the brain may reduce damage during seizures and promote recovery, according to study in mice

Seizures are like sudden electrical storms in the brain that can cause lasting damage. A set of immune cells in the brain called microglia may provide protection.

Synphane Gibbs-Shelton, Ph.D. Candidate in Pharmacology, University of Virginia • conversation
July 11, 2023 ~3 min

Blocking this gene slows heart scarring, failure

Blocking a specific gene in people in the early stages of cardiomyopathy could halt the development of scar tissue and delay heart failure.

Federico Graciano - Duke-NUS • futurity
Dec. 9, 2022 ~6 min

Harnessing the brain's immune cells to stave off Alzheimer's and other neurodegenerative diseases

Microglia, immune cells disguised as brain cells, are known as the janitors of the brain. Dialing up their usual duties just enough could provide an avenue to treat neurodegenerative disease.

Kristine Zengeler, Ph.D. Candidate in Neuroscience, University of Virginia • conversation
Dec. 7, 2022 ~9 min

Fewer key immune cells may contribute to Alzheimer’s

Can underproduction of key immune cells contribute to Alzheimer's? A new study suggests the answer is yes.

Andrew Smith-Rutgers • futurity
Nov. 30, 2022 ~5 min

What is inflammation? Two immunologists explain how the body responds to everything from stings to vaccination and why it sometimes goes wrong

Inflammation is a complicated and important part of how the immune system responds to threats to the body. But when the inflammatory response goes awry, it can lead to serious problems.

Mitzi Nagarkatti, Professor of Pathology, Microbiology and Immunology, University of South Carolina • conversation
Nov. 7, 2022 ~6 min


Long COVID-19 and other chronic respiratory conditions after viral infections may stem from an overactive immune response in the lungs

While a strong immune response is essential to fight against viral infection, an immune system that continues to stay active long after the virus has been cleared can lead to lung damage.

Harish Narasimhan, PhD Candidate in Immunology, University of Virginia • conversation
Aug. 4, 2022 ~7 min

Sepsis still kills 1 in 5 people worldwide – two ICU physicians offer a new approach to stopping it

Sepsis onset can be difficult to recognize, in part because its symptoms can mimic those of many other conditions. A treatment delay of even a few hours can make the difference between life and death.

Kristina E. Rudd, Assistant Professor of Critical Care Medicine, University of Pittsburgh Health Sciences • conversation
June 10, 2022 ~10 min

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