Your immune system makes its own antiviral drug − and it's likely one of the most ancient

The human body has been making antivirals for eons, long before scientists did. A protein in your cells called viperin produces molecules that work similarly to the COVID-19 antiviral remdesivir.

Neil Marsh, Professor of Chemistry and Biological Chemistry, University of Michigan • conversation
Oct. 11, 2023 ~8 min

Cell death is essential to your health − an immunologist explains when cells decide to die with a bang or take their quiet leave

Your cells die to keep you alive. Cell death does everything from fighting cancer cells and pathogens to forming your fingers and toes.

Zoie Magri, Ph.D. Candidate in Immunology, Tufts University • conversation
Oct. 4, 2023 ~8 min


How does fever help fight infections? There's more to it than even some scientists realize

The heat and chills that come with fever are not only uncomfortable but also metabolically costly. Increased body temperature, however, can make all the difference when you’re sick.

Joe Alcock, Professor of Emergency Medicine, University of New Mexico • conversation
Sept. 11, 2023 ~8 min

Molecule reduces inflammation in Alzheimer’s models

A potential new Alzheimer’s drug represses the harmful inflammatory response of the brain’s immune cells, reducing disease pathology, preserving neurons, and improving cognition in preclinical tests.

David Orenstein | The Picower Institute for Learning and Memory • mit
Sept. 5, 2023 ~8 min

A snapshot of cancer vaccine development

The Koch Institute’s Annual Symposium highlights emerging successes and challenges in the advancement of vaccines to prevent and treat cancer.

Bendta Schroeder | Koch Institute • mit
Aug. 15, 2023 ~11 min

Study finds a surprising new role for a major immune regulator

In addition to turning on genes involved in cell defense, the STING protein also acts as an ion channel, allowing it to control a wide variety of immune responses.

Anne Trafton | MIT News • mit
Aug. 3, 2023 ~8 min

Immune cells that fight cancer become exhausted within hours of first encountering tumors – new research

T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.

Michael Rudloff, MD-Ph.D. Candidate in Molecular Pathology and Immunology, Vanderbilt University • conversation
Aug. 3, 2023 ~6 min

Newly discovered bacterial communication system aids antimicrobial resistance

SMART researchers find the enzyne RlmN, which directly senses chemical and environmental stresses, can be targeted in drug development.

Singapore-MIT Alliance for Research and Technology • mit
Aug. 2, 2023 ~6 min


‘Ageing’ immune cell levels could predict how well we respond to vaccines

Cambridge scientists have identified a signature in the blood that could help predict how well an individual will respond to vaccines. The discovery, published

Cambridge University News • cambridge
June 27, 2023 ~4 min

Atlas of human brain blood vessels highlights changes in Alzheimer’s disease

MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.

Rachel Gordon | MIT CSAIL • mit
June 21, 2023 ~17 min

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