Immune cells that fight cancer become exhausted within hours of first encountering tumors – new research
T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.
Michael Rudloff, MD-Ph.D. Candidate in Molecular Pathology and Immunology, Vanderbilt University
• conversation
Aug. 3, 2023 • ~6 min
Aug. 3, 2023 • ~6 min
Gain-of-function research is more than just tweaking risky viruses – it's a routine and essential tool in all biology research
From cancer immunotherapy and antibiotics to GMO crops and pandemic surveillance, gain of function is a cornerstone of basic research.
Anice Lowen, Associate Professor of Microbiology and Immunology, Emory University •
conversation
May 8, 2023 • ~11 min
May 8, 2023 • ~11 min
Every cancer is unique – why different cancers require different treatments, and how evolution drives drug resistance
There is no one-size-fits-all approach to treating cancer. Understanding how cancer cells evolve could help researchers develop more effective drugs.
Monika Joshi, Associate Professor of Hematology and Oncology, Penn State •
conversation
May 1, 2023 • ~10 min
May 1, 2023 • ~10 min
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