Early imaging can reveal if melanoma immunotherapy will work

"...imaging tumors early can improve how clinicians develop personalized treatment plans for each patient."

Kelsey Geesler - Penn • futurity
Feb. 13, 2024 ~5 min

Why cancer immunotherapy can cause colitis

"Once we identified the mechanism causing the colitis, we could then develop ways to overcome this problem..."

Nicole Fawcett-Michigan • futurity
Jan. 8, 2024 ~5 min


‘Reprogrammed’ cells may help glioblastoma resist treatment

Glioblastoma is one of the most treatment-resistant cancers. A new study offers clues as to how it can aggressively resist immunotherapy.

Brandi Wampler-Notre Dame • futurity
Dec. 13, 2023 ~5 min

How serious is FDA warning about revolutionary blood-cancer treatment?

Dana-Farber Cancer Institute researcher details promise, peril of CAR T-cell therapy, which enlists body’s immune system to fight disease.

Alvin Powell • harvard
Dec. 7, 2023 ~10 min

Cancer drug gets immune cells back in the fight

In mouse models of different cancers, a new drug slowed tumor growth, extended lifespan, and boosted the efficacy of immunotherapy.

Christine Sinatra-UT Austin • futurity
Oct. 9, 2023 ~6 min

Immune cells that fight cancer become exhausted within hours of first encountering tumors – new research

T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.

Michael Rudloff, MD-Ph.D. Candidate in Molecular Pathology and Immunology, Vanderbilt University • conversation
Aug. 3, 2023 ~6 min

Engineered ‘tails’ tame killer T cells for immunotherapy

Fusing a molecular tail onto the engineered T cells used in immunotherapy can inhibit their proclivity to attack each other, say researchers.

Bill Hathaway-Yale • futurity
July 28, 2023 ~3 min

New Hodgkin lymphoma treatment shines in clinical trial

"We hypothesized that the newer treatment would turn out to be most beneficial for patients, but the magnitude of the benefit exceeded our expectations."

Leslie Orr-Rochester • futurity
June 9, 2023 ~6 min


Gain-of-function research is more than just tweaking risky viruses – it's a routine and essential tool in all biology research

From cancer immunotherapy and antibiotics to GMO crops and pandemic surveillance, gain of function is a cornerstone of basic research.

Anice Lowen, Associate Professor of Microbiology and Immunology, Emory University • conversation
May 8, 2023 ~11 min

Every cancer is unique – why different cancers require different treatments, and how evolution drives drug resistance

There is no one-size-fits-all approach to treating cancer. Understanding how cancer cells evolve could help researchers develop more effective drugs.

Monika Joshi, Associate Professor of Hematology and Oncology, Penn State • conversation
May 1, 2023 ~10 min

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