What is metabolism? A biochemist explains how different people convert energy differently − and why that matters for your health

An elite athlete’s metabolism mostly looks different from a patient with COVID-19 − but their occasional similarities can reveal important insights into health and disease.

Travis Nemkov, Assistant Research Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus • conversation
April 4, 2024 ~9 min

Customizing mRNA is easy, and that's what makes it the next frontier for personalized medicine − a molecular biologist explains

From COVID-19 vaccines to cancer treatments and beyond, the flexibility of mRNA-based therapies gives them the potential to prevent and treat many types of diseases.

Angie Hilliker, Associate Professor of Biology, University of Richmond • conversation
Dec. 12, 2023 ~9 min


Zooming across time and space simultaneously with superresolution to understand how cells divide

Superresolution microscopy allowed researchers to view cells at the molecular level. Improvements on the technique can help study the building blocks of complex cell processes over time.

Somin Lee, Assistant Professor of Electrical & Computer Engineering, Biomedical Engineering, University of Michigan • conversation
July 20, 2023 ~6 min

Bringing Stone Age genomic material back to life

Scientific breakthroughs will enable exploration of Earth’s biochemical past, with hopes of discovering new therapeutic molecules.

Christy DeSmith • harvard
May 4, 2023 ~6 min

How does RNA know where to go in the city of the cell? Using cellular ZIP codes and postal carrier routes

Making sure RNA molecules are in the right place at the right time in a cell is critical to development and normal function. Researchers are figuring out exactly how they get to where they need to go.

Matthew Taliaferro, Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus • conversation
March 6, 2023 ~9 min

Visualizing the inside of cells at previously impossible resolutions provides vivid insights into how they work

Many microscopy techniques have won Nobel Prizes over the years. Advancements like cryo-ET that allow scientists to see the individual atoms of cells can reveal their biological functions.

Jeremy Berg, Professor of Computational and Systems Biology, Associate Senior Vice Chancellor for Science Strategy and Planning, University of Pittsburgh • conversation
Jan. 6, 2023 ~7 min

Helping the liver regenerate itself could give patients with end-stage liver disease a treatment option besides waiting for a transplant

Liver transplant waitlists can range from 30 days to over five years. Developing treatments that spur liver regeneration could help reduce demand for scarce organs.

Satdarshan Monga, Professor of Pathology and Medicine, University of Pittsburgh Health Sciences • conversation
Oct. 14, 2022 ~7 min

Nobel Prize: How click chemistry and bioorthogonal chemistry are transforming the pharmaceutical and material industries

Click and bioorthogonal chemistry has enabled researchers to closely study how molecules work in their natural state in living organisms, with applications that span from cancer treatment to polymers.

Heyang (Peter) Zhang, PhD Candidate in Chemistry, University at Buffalo • conversation
Oct. 7, 2022 ~6 min


Gonorrhea became more drug resistant while attention was on COVID-19 – a molecular biologist explains the sexually transmitted superbug

The US currently has only one antibiotic available to treat gonorrhea – and it’s becoming less effective.

Kenneth Keiler, Professor of Biochemistry and Molecular Biology, Penn State • conversation
Oct. 5, 2022 ~8 min

*Yorkicystis*, the 500 million-year-old relative of starfish that lost its skeleton

The discovery of a unique 510 million-year-old fossil in a Pennsylvania churchyard offers new clues into how early life evolved on Earth.

Samuel Zamora, Científico Titular (Paleontólogo), Instituto Geológico y Minero de España (IGME - CSIC) • conversation
May 24, 2022 ~8 min

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