Fewer deaths, new substances and evolving treatments in Philly’s opioid epidemic − 4 essential reads

Philly’s opioid addiction crisis is constantly evolving. Local health care workers and researchers explain some of the latest substances, side effects and treatments.

Kate Kilpatrick, Philadelphia Editor • conversation
March 17, 2025 ~7 min

Dozens of US adolescents are dying from drug overdoses every month − an expert on substance use unpacks the grim numbers with 3 charts

Among adolescents, boys are more likely to die of an overdose than girls, and using combinations of drugs substantially raises the risk of an overdose.

Ty Schepis, Professor of Psychology, Texas State University • conversation
Nov. 27, 2023 ~7 min


White patients are more likely than Black patients to be given opioid medication for pain in US emergency departments

Undertreated pain can result in unnecessary suffering and a greater likelihood of long-term chronic pain.

Sofia Stathi, Professor of Social Psychology, University of Greenwich • conversation
Oct. 27, 2023 ~5 min

Study finds ‘startling’ inequities in end-of-life opioid treatment

Investigators at Harvard-affiliated Dana-Farber Cancer Institute reported Black and Hispanic patients who had poor-prognosis cancer were less likely than white patients to receive opioid medications.

Harvard Gazette • harvard
Jan. 17, 2023 ~6 min

The opioid crisis isn’t just the Sacklers’ fault – and making Purdue Pharma pay isn’t enough on its own to fix the pharmaceutical industry’s deeper problems

Making them pay is important but it’s not going to stop drugmakers from endangering public health.

David Herzberg, Associate Professor of History, University at Buffalo • conversation
July 26, 2022 ~11 min

Why opting out of opioids can be dangerous in the operating room

Non-opioid directives allow patients to refuse opioids in all health care settings. For surgical procedures that require anesthesia, however, this may do more harm than good.

Paul Edward Hilliard, Clinical Associate Professor of Anesthesiology, University of Michigan • conversation
June 10, 2022 ~8 min

New tool models evolution of opioid crisis

To help combat the opioid crisis, researchers have developed a tool, known as SOURCE, which taps national data on opioids to track stages of use and misuse, including use initiation, treatment, relapse, and death by overdose.

Harvard Gazette • harvard
June 3, 2022 ~4 min

In research studies and in real life, placebos have a powerful healing effect on the body and mind

Drug manufacturers often shun the use of placebos in clinical trials. But research suggests that placebos could play an important role in the treatment of depression, pain and other maladies.

Hans Schroder, Clinical Assistant Professor of Psychiatry, University of Michigan • conversation
Feb. 11, 2022 ~11 min


MGH expert responds to 100,000 overdose deaths

Sarah Wakeman says that CDC report highlights need for U.S. to radically rethink response to opioid epidemic.

Colleen Walsh • harvard
Nov. 29, 2021 ~10 min

How the pandemic helped spread fentanyl across the US and drive opioid overdose deaths to a grim new high

The number of fatal drug overdoses in the US over a 12-month period has surpassed 100,000 for the first time. Fentanyl is the main driver of the spike in deaths.

Andrew Kolodny, Co-Director of Opioid Policy Research, Brandeis University • conversation
Nov. 22, 2021 ~5 min

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