Technique recovers lost single-cell RNA-sequencing information

Boosting the efficiency of single-cell RNA-sequencing helps reveal subtle differences between healthy and dysfunctional cells.

Anne Trafton | MIT News Office • mit
Oct. 13, 2020 ~7 min

Tags: chemistry broad-institute ragon-institute research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes

A step toward a universal flu vaccine

With computer models and lab experiments, researchers are working on a strategy for vaccines that could protect against any influenza virus.

Anne Trafton | MIT News Office • mit
Oct. 7, 2020 ~8 min

Tags: influenza physics chemistry medicine ragon-institute vaccines disease viruses research school-of-engineering school-of-science national-science-foundation-nsf national-institutes-of-health-nih chemical-engineering institute-for-medical-engineering-and-sciences-imes

Engineers use “DNA origami” to identify vaccine design rules

In lab tests, virus-like DNA structures coated with viral proteins provoke a strong immune response in human B cells.

Anne Trafton | MIT News Office • mit
June 29, 2020 ~7 min

Tags: covid-19 broad-institute ragon-institute vaccines research school-of-engineering national-institutes-of-health-nih materials-science-and-engineering dmse biological-engineering koch-institute

Vaccines can protect against COVID-19 in animal models, study says

Harvard-affiliated Beth Israel Deaconess Medical Center has developed vaccines — currently being tested in animal models — that are designed to train the body’s immune system to recognize the virus swiftly upon exposure and respond quickly to disable it.

Harvard Gazette • harvard
May 20, 2020 ~8 min

Tags: covid-19 coronavirus harvard-medical-school health-medicine ragon-institute vaccine sars-cov-2 dan-h-barouch re-infection

Researchers identify cells likely targeted by Covid-19 virus

Study finds specific cells in the lungs, nasal passages, and intestines that are more susceptible to infection.

Anne Trafton | MIT News Office • mit
April 22, 2020 ~9 min

Tags: chemistry covid-19 broad-institute ragon-institute disease viruses research school-of-engineering school-of-science national-institutes-of-health-nih koch-institute institute-for-medical-engineering-and-science-imes

Ragon Institute receives major gift to expand research into autoimmune diseases

Immunology research at the Ragon Institute of MGH, MIT, and Harvard has advanced an HIV vaccine into the clinic, and will diversify thanks to a major gift from Phillip T. and Susan M. Ragon.

Mary Todd Bergman • harvard
Sept. 19, 2019 ~9 min

Tags:  science-technology  public-health  basic-research  immunology  bruce-walker  phillip-t-terry-and-susan-m-ragon  ragon-institute  vaccines

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