Researchers uncover a new CRISPR-like system in animals that can edit the human genome

The first RNA-guided DNA-cutting enzyme found in eukaryotes, Fanzor could one day be harnessed to edit DNA more precisely than CRISPR/Cas systems.

Leah Eisenstadt | McGovern Institute for Brain Research | Broad Institute • mit
June 28, 2023 ~7 min

Ancient viruses left bits of RNA in coral symbiont DNA

Marine biologists have discovered the remnants of ancient RNA viruses embedded in the DNA of symbiotic organisms living inside reef-building corals.

Jade Boyd-Rice • futurity
June 5, 2023 ~7 min


Gene therapy helps combat some forms of blindness – and ongoing clinical trials are looking to extend these treatments to other diseases

Genetics expert Jean Bennett explains how gene therapy is being used to treat certain forms of inherited blindness.

Jean Bennett, Professor Emeritus of Ophthalmology; Cell and Developmental Biology, University of Pennsylvania • conversation
May 12, 2023 ~8 min

A new control switch could make RNA therapies easier to program

Using this approach, researchers hope to deliver therapeutic RNA molecules selectively to cancer cells or other target cells.

Anne Trafton | MIT News Office • mit
March 15, 2023 ~7 min

How does RNA know where to go in the city of the cell? Using cellular ZIP codes and postal carrier routes

Making sure RNA molecules are in the right place at the right time in a cell is critical to development and normal function. Researchers are figuring out exactly how they get to where they need to go.

Matthew Taliaferro, Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus • conversation
March 6, 2023 ~9 min

Were viruses around on Earth before living cells emerged? A microbiologist explains

Fossil evidence of how the earliest life on Earth came to be is hard to come by. But scientists have come up with a few theories based on the microbes, viruses and prions existing today.

Kenneth Noll, Professor Emeritus of Microbiology, University of Connecticut • conversation
Feb. 20, 2023 ~7 min

Researchers map brain cell changes in Alzheimer’s disease

Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue.

Allessandra DiCorato | Broad Institute • mit
Feb. 2, 2023 ~7 min

How Huntington’s disease affects different neurons

A new study identifies cells that are the most vulnerable within a brain structure involved in mood and movement.

Anne Trafton | MIT News Office • mit
Jan. 20, 2023 ~7 min


New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.

David Orenstein | Picower Institute for Learning and Memory • mit
Jan. 18, 2023 ~6 min

Vaccination to prevent dementia? New research suggests one way viral infections can accelerate neurodegeneration

Inflammation and damage to the olfactory system from shingles, COVID-19 and herpes infections may contribute to Alzheimer’s disease.

Maria Nagel, Professor of Neurology and Ophthalmology, University of Colorado Anschutz Medical Campus • conversation
Jan. 18, 2023 ~9 min

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