Immune cells can adapt to invading pathogens, deciding whether to fight now or prepare for the next battle

When faced with a threat, T cells have the decision-making flexibility to both clear out the pathogen now and ready themselves for a future encounter.

Hao Yuan Kueh, Associate Professor of Bioengineering, University of Washington • conversation
March 8, 2024 ~6 min

How serious is FDA warning about revolutionary blood-cancer treatment?

Dana-Farber Cancer Institute researcher details promise, peril of CAR T-cell therapy, which enlists body’s immune system to fight disease.

Alvin Powell • harvard
Dec. 7, 2023 ~10 min


Immune health is all about balance – an immunologist explains why both too strong and too weak an immune response can lead to illness

Dietary supplements claim to be able to ‘boost your immune system’ to combat disease. But attaining immune balance through a healthy lifestyle and vaccination is a safer bet to keep in good health.

Aimee Pugh Bernard, Assistant Professor of Immunology and Microbiology, University of Colorado Anschutz Medical Campus • conversation
Nov. 20, 2023 ~6 min

New study explains how exercise reduces chronic inflammation

Research in mice shows that exercise mobilizes inflammation-countering T cells, lowering levels of interferon — a key driver of chronic inflammation, inflammatory diseases, and aging.

Ekaterina Pesheva • harvard
Nov. 3, 2023 ~8 min

T cell tweak enhances immune system memory

New findings may support the development of more effective vaccines and therapeutics against influenza, researchers report.

Brian Consiglio-U. Missouri • futurity
Sept. 28, 2023 ~4 min

Immune cells that fight cancer become exhausted within hours of first encountering tumors – new research

T cells recognize and kill cancer cells but quickly lose their effectiveness. This fast dysfunction may help explain why immunotherapy doesn’t lead to long-term remission for many patients.

Michael Rudloff, MD-Ph.D. Candidate in Molecular Pathology and Immunology, Vanderbilt University • conversation
Aug. 3, 2023 ~6 min

Asymptomatic COVID-19 is linked to a gene variant that boosts immune memory after exposure to prior seasonal cold viruses

Researchers found that people with a specific gene variant were two to eight times more likely to not have symptoms after infection.

Danillo Augusto, Assistant Professor of Biological Sciences, University of North Carolina – Charlotte • conversation
July 19, 2023 ~5 min

Gut microbes found to help mend damaged muscles in mice

A Harvard-led study shows that the gut microbiota acts as the training camp for a class of immune cells that are recruited to heal muscle injury.

Ilima Loomis • harvard
March 6, 2023 ~9 min


Moderna's experimental cancer vaccine treats but doesn't prevent melanoma – a biochemist explains how it works

Preventive and therapeutic vaccines both train the immune system to fight disease, but they are used in different ways.

Mark R. O'Brian, Professor and Chair of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo • conversation
Jan. 17, 2023 ~8 min

Anti-cancer CAR-T therapy reengineers T cells to kill tumors – and researchers are expanding the limited types of cancer it can target

Immunotherapy has the potential to eliminate tumors, but works best for select patients. Engineering T cells to bypass cancer’s defenses could help expand treatment eligibility to more patients.

Gregory Allen, Assistant Professor of Medicine, University of California, San Francisco • conversation
Dec. 15, 2022 ~8 min

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