Many medications affect more than one target in the body – some drug designers are embracing the 'side effects' that had been seen as a drawback

Many approved drugs work on the body in ways that researchers still aren’t entirely clear about. Seeing this as an opportunity instead of a flaw may lead to better treatments for complex conditions.

Gregory Way, Assistant Professor of Biochemistry and Molecular Genetics, University of Colorado Anschutz Medical Campus • conversation
July 11, 2022 ~9 min

How do drugs know where to go in the body? A pharmaceutical scientist explains why some medications are swallowed while others are injected

From tablets and patches to ointments and infusions, the best way to deliver a drug is the one that gets the right amount to the right place.

Tom Anchordoquy, Professor of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus • conversation
June 17, 2022 ~7 min


What is Paxlovid and how will it help the fight against coronavirus? An infectious diseases physician answers questions on the COVID-19 pill

An infections disease doctor discusses the use, benefits and availability of a drug to prevent severe COVID-19.

Patrick Jackson, Assistant Professor of Infectious Diseases, University of Virginia • conversation
April 28, 2022 ~6 min

Discovering new drugs is a long and expensive process – chemical compounds that dupe screening tools make it even harder

While technological advancements have quickened the drug discovery process, some chemical compounds remain a common thorn in a researcher’s side.

Martin Clasby, Research Assistant Professor of Medicinal Chemistry, University of Michigan Medical School • conversation
April 21, 2022 ~6 min

How the pandemic helped spread fentanyl across the US and drive opioid overdose deaths to a grim new high

The number of fatal drug overdoses in the US over a 12-month period has surpassed 100,000 for the first time. Fentanyl is the main driver of the spike in deaths.

Andrew Kolodny, Co-Director of Opioid Policy Research, Brandeis University • conversation
Nov. 22, 2021 ~5 min

Why prescription drugs can work differently for different people

The same dose of a drug can have varying degrees of effectiveness and safety depending on how well the liver can metabolize it.

C. Michael White, Distinguished Professor and Head of the Department of Pharmacy Practice, University of Connecticut • conversation
Oct. 4, 2021 ~9 min

Drugs, robots and the pursuit of pleasure – why experts are worried about AIs becoming addicts

When people think about how AI might ‘go wrong’, most probably picture malevolent computers trying to cause harm. But what if we should be more worried about them seeking pleasure?

Anders Sandberg, James Martin Research Fellow, Future of Humanity Institute & Oxford Martin School, University of Oxford • conversation
Sept. 14, 2021 ~31 min

Poison or cure? Traditional Chinese medicine shows that context can make all the difference

The usefulness of a drug is typically measured by its active ingredient. But traditional Chinese medicine shows that there’s more to healing than using the right chemical.

Yan Liu, Assistant Professor of History, University at Buffalo • conversation
Aug. 23, 2021 ~9 min


Rat poison is just one of the potentially dangerous substances likely to be mixed into illicit drugs

In an effort to reduce costs, drugmakers and dealers often cut, or adulterate, recreational drugs with substances that have been banned by the FDA.

C. Michael White, Distinguished Professor and Head of the Department of Pharmacy Practice, University of Connecticut • conversation
Aug. 16, 2021 ~7 min

When did humans start experimenting with alcohol and drugs?

Today, Homo sapiens regularly use psychoactive chemicals to modify the mind – but how did it all begin?

Nicholas R. Longrich, Senior Lecturer in Evolutionary Biology and Paleontology, University of Bath • conversation
July 16, 2021 ~9 min

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