'Normal' human body temperature is a range around 98.6 F – a physiologist explains why

'Normal' body temperature varies from person to person by age, time of day, where it's measured, and even menstrual cycle. External conditions also influence your thermometer reading.

JohnEric Smith, Associate Professor of Exercise Physiology, Mississippi State University • conversation
June 16, 2020 ~9 min

Tags: coronavirus metabolism inflammation sars-cov-2 fever infection immune-response temperature body-temperature warmblood warm-bloodedness

Am I immune to COVID-19 if I have antibodies?

If you have had COVID-19 already, are you protected from another bout of the illness? And is the presence of antibodies in your blood a guarantee of immunity?

William Petri, Professor of Medicine, University of Virginia • conversation
June 12, 2020 ~6 min

Tags: covid-19 immune-system sars-cov-2 immunity immune-response antibody spike-protein

COVID-19's deadliness for men is revealing why researchers should have been studying immune system sex differences years ago

Why does COVID-19 hit men harder than women? Is the disparity in mortality rates due male hormones or an underlying difference in the male versus female immune system?

Adam Moeser, Matilda R. Wilson Endowed Chair, Associate Professor of Large Animal Clinical Sciences, Michigan State University • conversation
June 9, 2020 ~8 min

Tags:  covid-19  immune-system  pandemic  sars-cov-2  immune-response  testosterone  estrogen  androgen

Blocking the deadly cytokine storm is a vital weapon for treating COVID-19

We blame the coronavirus for the thousands of deaths, but it is actually a hyperactive immune reaction that is the cause of death. An immunologist explains.

Alexander (Sasha) Poltorak, Professor of Immunology, Tufts University • conversation
May 20, 2020 ~7 min

Tags: covid-19 coronavirus inflammation immune-system pandemic sars-cov-2 viruses immune-response pathogen

What needs to go right to get a coronavirus vaccine in 12-18 months

Vaccine development is usually a long process. The coronavirus pandemic is forcing researchers to innovate and test potential vaccines faster than ever before.

Marcos E. García-Ojeda, Professor of Molecular and Cell Biology, University of California, Merced • conversation
May 8, 2020 ~10 min

Tags: dna health coronavirus immune-system rna fda vaccines sars-cov-2 food-and-drug-administration immune-response coronavirus-vaccine immune clinical-trials

Coronavirus linked to greater risk of life-threatening infection in people with obesity

Over-active immune response might be behind higher rates of life-threatening COVID-19 infections in patients with obesity.

Noel Caplice, University College Cork • conversation
May 6, 2020 ~6 min

Tags:  covid-19  coronavirus  obesity  immune-response  cytokines  obese

Coronavirus 'cytokine storm': this over-active immune response could be behind some fatal cases of COVID-19

Cytokines ensure our immune system responds effectively to pathogens in our bodies. But in some cases, cytokines can cause the immune system to over-react.

Robbie Baldock, Lecturer in Biochemistry, Solent University • conversation
April 28, 2020 ~6 min

Tags:  covid-19  coronavirus  immune-system  ventilators  immune-response  cytokines

A coronavirus vaccine that wouldn't require a shot

University of Pittsburgh researchers are developing a vaccine patch for COVID-19 that is as easy to apply as a Band-Aid.

Louis Falo, Professor of Dermatology, University of Pittsburgh • conversation
April 8, 2020 ~5 min

Tags:  covid-19  coronavirus  immune-system  pandemic  vaccines  sars-cov-2  severe-acute-respiratory-syndrome-sars  immune-response  middle-east-respiratory-syndrome-mers

Older people are at more risk from COVID-19 because of how the immune system ages

Different demographics are more or less vulnerable to serious complications from the coronavirus. A virologist explains the aging-related changes in how immune systems work that are to blame.

Brian Geiss, Associate Professor of Microbiology, Immunology & Pathology, Colorado State University • conversation
March 19, 2020 ~7 min

Tags:  covid-19  coronavirus  immune-system  t-cells  immunology  aging  sars-cov-2  immunity  coronavirus-2020  new-coronavirus  adaptive-immune-response  innate-immune-response  immune-response  white-blood-cells  t-cell

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