New drug-detecting tool could help save lives

The landscape of the illegal drug trade changes constantly, particularly amid the current opioid crisis. Law-enforcement officers regularly find or confiscate pills, powders, and other substances and need to know their composition as quickly as possible to determine legal charges and sometimes to issue lifesaving warnings. Carfentanil is a case in point. This cousin to […]

Caitlin McDermott-Murphy | Nov. 13, 2019 | harvard
~7 mins   

Tags: health-medicine basic-research caitlin-mcdermott-murphy cambridge carfentanil chemistry christoffer-abrahamsson dea drug-analysis drug-enforcement-administration engineering-technology fas fentanyl forensic-science george-whitesides law-enforcement opioid-epidemic

Better delivery system for sending chemo to cancerous lung tissue

A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

Lindsay Brownell | Nov. 13, 2019 | harvard
~8 mins   

Tags: science-technology basic-research biodegradable-polymer cancer chemotherapy elect engineering erythrocyte-leveraged-chemotherapy john-a-paulson-school-of-engineering-and-applied-sciences lung-cancer trojan-horse wyss-institute-for-biologically-inspired-engineering

How the brain regulates variability in motor functions

Research suggests that errors resulting from variability in motor function are a feature, not a bug, of our nervous system and play a critical role in learning.

Leah Burrows | Nov. 7, 2019 | harvard
~5 mins   

Tags: science-technology basic-research motor-function nervous-system regulate-variability variability

Exercise found to block chronic inflammation in mice

A new study identifies a molecular connection between exercise and inflammation that takes place in the bone marrow and highlights a previously unappreciated role of leptin in exercise-mediated cardiovascular protection.

Harvard Gazette | Nov. 7, 2019 | harvard
~4 mins   

Tags: health-medicine artery-clogging-blockages basic-research chronic-inflammation heart-disease hematopoietic-stem hspc leptin leukocytes

Ragon Institute receives major gift to expand research into autoimmune diseases

Immunology research at the Ragon Institute of MGH, MIT, and Harvard has advanced an HIV vaccine into the clinic, and will diversify thanks to a major gift from Phillip T. and Susan M. Ragon.

Mary Todd Bergman | Sept. 19, 2019 | harvard
~9 mins   

Tags: science-technology basic-research bruce-walker immunology phillip-t-terry-and-susan-m-ragon public-health ragon-institute vaccines

AAAS Golden Goose Awards honor basic research that benefits humankind

Harvard-trained researchers win Golden Goose Awards from the American Association for the Advancement of Science.

Mary Todd Bergman | Sept. 11, 2019 | harvard
~10 mins   

Tags: science-technology alumni american-association-for-the-advancement-of-science awards basic-research david-sachar federal-relations golden-goose-award immunology noel-rose

Islet-on-a-chip technology streamlines diabetes research

Islet-on-a-chip technology allows clinicians to easily determine the therapeutic value of beta cells for any given patient.

Mary Bergman | Aug. 29, 2019 | harvard
~6 mins   

Tags: science-technology basic-research biotechnology diabetes douglas-a-melton organ-on-a-chip otd type-2-diabetes

Exposing how pancreatic cancer does its dirty work

New research has found that pancreatic cancer actively destroys nearby blood vessels and replaces them with cancerous cells, blocking chemotherapy from reaching tumors. This insight could lead to new treatments that act by preventing cancer’s colonization of blood vessels.

Lindsay Brownell | Aug. 28, 2019 | harvard
~8 mins   

Tags: science-technology angiogenesis basic-research cancer-cells endothelial-cells engineering harvards-wyss-institute-for-biologically-inspired-engineering immune-cells organ-on-chip pancreatic-cancer tumors

Growing organoids uncovers how cells become organs

Tiny sensors are embedded into stretchable, integrated mesh that grows with the developing tissue, allowing scientists to track how cells grow into organs.

Leah Burrows | Aug. 16, 2019 | harvard
~3 mins   

Tags: science-technology basic-research charles-m-lieber cyborg-organoids jia-liu john-a-paulson-school-of-engineering-and-applied-sciences leah-burrows nano-letters organoids

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