Broad Institute races to enable coronavirus testing

Facing a pandemic, scientific and administrative teams across the Broad Institute raced to enable coronavirus testing in a matter of days.

Leah Eisenstadt • harvard
March 30, 2020 ~19 min

 science-technology  covid-19  coronavirus  broad-institute  broad-institute-of-mit-and-harvard  facing-a-pandemic  scientific-and-administrative-teams-across-the-institute-raced-to-enable-coronavirus-testing  testing

Harvard experts say Massachusetts may need 1.4 million COVID tests

Massachusetts may need 1.4 million COVID-19 tests and ramp up to tens of thousands given a day, Harvard experts said.

Alvin Powell • harvard
March 13, 2020 ~6 min

 covid-19  coronavirus  harvard-medical-school  health-medicine  brigham-and-womens-hospital  alvin-powell  harvard-th-chan-school-of-public-health  massachusetts-general-hospital  george-daley  broad-institute-of-mit-and-harvard  pardis-sabeti  ed-markey  eric-rubin  peter-slavin

Personalized blood biopsies may provide signal of cancer recurrence

Researchers have designed personalized blood biopsies that offer the potential of an early warning signal of breast cancer recurrence.

Karen Zusi • harvard
March 13, 2020 ~8 min

 science-technology  breast-cancer  basic-research  dana-farber-cancer-institute  broad-institute-of-mit-and-harvard  blood-biopsies  gerstner-center-for-cancer-diagnostics  tumor-mutations

The story behind the mumps outbreaks of 2016-17

Studying the mumps virus genomes in 2016 and 2017 filled in gaps about how the disease was spreading in Massachusetts and elsewhere in the U.S.

Karen Zusi • harvard
Feb. 11, 2020 ~8 min

 science-technology  engineering  basic-research  broad-institute-of-mit-and-harvard  pardis-sabeti  plos-biology  viral-genomics

Big step toward identifying all cancer-causing genetic mutations

An international team of 1,300 scientists has generated the most complete cancer genome map to date, bringing researchers closer to identifying all major cancer-causing genetic mutations.

Stephanie McPherson • harvard
Feb. 5, 2020 ~12 min

 science-technology  engineering  bioengineering  basic-research  broad-institute-of-mit-and-harvard  cancer-genome-map  cancer-causing-genetic-mutations  icgctcga-pan-cancer-analysis-of-whole-genomes-project  pan-cancer-project  whole-cancer-genomes

Preventing sudden cardiac death through gene sequencing

Researchers have determined that genetic testing could identify those at risk for cardiac death prior to any symptoms.

Harvard Gazette • harvard
Nov. 16, 2019 ~4 min

 science-technology  basic-research  broad-institute-of-mit-and-harvard  cardiac-death  gene-sequencing

Researchers can program a CRISPR enzyme to kill viruses in human cells

Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Karen Zusi • harvard
Oct. 10, 2019 ~5 min

 science-technology  crispr  ebola  rna  virus  broad-institute-of-mit-and-harvard  carver  cas13-enzyme  cas13-assisted-restriction-of-viral-expression-and-readout  flu  rna-based-viruses  sherlock  zika