At-home COVID-19 test study launches in Boston

The TestBoston study will facilitate at-home testing on 10,000 people for both the SARS-CoV-2 virus and antibodies against it to increase access to testing and surveillance.

Haley Bridger • harvard
Oct. 6, 2020 ~5 min

covid-19 health-medicine brigham-and-womens-hospital broad-institute sars-cov-2 covid-tests testboston

Lessons from a pandemic

Seven researchers discuss the importance of COVID-19 research and pandemic preparedness, the value of teamwork, and the fragility of life.

lan Mochari, Namrata Sengupta, Kelsey Tsipis • harvard
July 17, 2020 ~17 min

covid-19 coronavirus pandemic health-medicine broad-institute anna-greka benjamin-gewurz deb-hung marcia-goldberg michael-gillette pradeep-natarajan roby-bhattacharyya



Synthetic microbial system developed to find objects’ origin

DNA-barcoded microbial spores can trace origin of objects, agricultural products.

Kevin Jiang • harvard
June 4, 2020 ~10 min

science-technology basic-research broad-institute sherlock probiotic dna-barcodes dna-barcoded-microbial-system foodborne-illnesses

A connection between ancestry and the molecular makeup of cancer

A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.

Rob Levy • harvard
May 11, 2020 ~7 min

cancer basic-research health-medicine tumors broad-institute human-genome-project ancestry nci-cancer-genome-analysis-network

New technology could provide rapid detection of COVID-19

The CRISPR-based molecular diagnostics chip’s capacity ranges from detecting a single type of virus in more than 1,000 samples at a time to searching a small number of samples for more than 160 different viruses, including the COVID-19 virus.

Karen Zusi • harvard
April 29, 2020 ~8 min

science-technology engineering covid-19 basic-research broad-institute carmen combinatorial-arrayed-reactions-for-multiplexed-evaluation-of-nucleic-acids crispr-based

Broad Institute races to enable coronavirus testing

Facing a pandemic, scientific and administrative teams across the Broad Institute raced to enable coronavirus testing in a matter of days.

Leah Eisenstadt • harvard
March 30, 2020 ~19 min

 science-technology  covid-19  coronavirus  broad-institute  broad-institute-of-mit-and-harvard  facing-a-pandemic  scientific-and-administrative-teams-across-the-institute-raced-to-enable-coronavirus-testing  testing

How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy • harvard
Feb. 14, 2020 ~7 min

 science-technology  dna  chemistry  crispr  genome  chemistry-and-chemical-biology  rna  gene-editing  broad-institute  caitlin-mcdermott-murphy  cas9  base-editing  base-editors  biotechnology-nature  david-liu  genetic-disease  genetic-engineering  sickle-cell-anemia

Brigham, Broad Institute researchers ID molecules that rein in CRISPR systems

Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.

Karen Zusi • harvard
May 2, 2019 ~5 min

 science-technology  crispr  cell  brigham-and-womens-hospital  gene-editing  amit-choudhary  broad-institute  cas-enzymes

/

2