A connection between ancestry and the molecular makeup of cancer

A new study takes the most comprehensive look to date at the connection between the ancestry and the molecular makeup of cancer.

Rob Levy • harvard
May 11, 2020 ~7 min

Tags: health-medicine ancestry basic-research broad-institute cancer human-genome-project nci-cancer-genome-analysis-network tumors

New technology could provide rapid detection of COVID-19

The CRISPR-based molecular diagnostics chip’s capacity ranges from detecting a single type of virus in more than 1,000 samples at a time to searching a small number of samples for more than 160 different viruses, including the COVID-19 virus.

Karen Zusi • harvard
April 29, 2020 ~8 min

Tags: science-technology basic-research broad-institute carmen combinatorial-arrayed-reactions-for-multiplexed-evaluation-of-nucleic-acids covid-19 crispr-based engineering

Harvard scientists work to find coronavirus treatment

As the pandemic intensifies, Harvard scientists work to find a treatment.

Juan Siliezar • harvard
March 30, 2020 ~14 min

Tags:  health-medicine  brigham-and-womens-hospital  christoph-gorgulla  coronavirus  covid-19  drug-repurposing-hub-of-the-broad-institute-of-mit-and-harvard  francisco-marty  george-church  haribabu-arthanari  harvard-medical-school  harvard-th-chan-school-of-public-health  jonathan-abraham  libby-hohmann  mark-namchuk  massachusetts-consortium-on-pathogen-readiness  massachusetts-general-hospital  remdesivir  sarah-fortune  wyss-institute-for-biologically-inspired-engineering

Broad Institute races to enable coronavirus testing

Facing a pandemic, scientific and administrative teams across the Broad Institute raced to enable coronavirus testing in a matter of days.

Leah Eisenstadt • harvard
March 30, 2020 ~19 min

Tags:  science-technology  broad-institute  broad-institute-of-mit-and-harvard  coronavirus  covid-19  facing-a-pandemic  scientific-and-administrative-teams-across-the-institute-raced-to-enable-coronavirus-testing  testing

Harvard experts say Massachusetts may need 1.4 million COVID tests

Massachusetts may need 1.4 million COVID-19 tests and ramp up to tens of thousands given a day, Harvard experts said.

Alvin Powell • harvard
March 13, 2020 ~6 min

Tags:  health-medicine  alvin-powell  brigham-and-womens-hospital  broad-institute-of-mit-and-harvard  coronavirus  covid-19  ed-markey  eric-rubin  george-daley  harvard-medical-school  harvard-th-chan-school-of-public-health  massachusetts-general-hospital  pardis-sabeti  peter-slavin

Personalized blood biopsies may provide signal of cancer recurrence

Researchers have designed personalized blood biopsies that offer the potential of an early warning signal of breast cancer recurrence.

Karen Zusi • harvard
March 13, 2020 ~8 min

Tags:  science-technology  basic-research  blood-biopsies  breast-cancer  broad-institute-of-mit-and-harvard  dana-farber-cancer-institute  gerstner-center-for-cancer-diagnostics  tumor-mutations

How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy • harvard
Feb. 14, 2020 ~7 min

Tags:  science-technology  base-editing  base-editors  biotechnology-nature  broad-institute  caitlin-mcdermott-murphy  cas9  chemistry  chemistry-and-chemical-biology  crispr  david-liu  dna  gene-editing  genetic-disease  genetic-engineering  genome  rna  sickle-cell-anemia

The story behind the mumps outbreaks of 2016-17

Studying the mumps virus genomes in 2016 and 2017 filled in gaps about how the disease was spreading in Massachusetts and elsewhere in the U.S.

Karen Zusi • harvard
Feb. 11, 2020 ~8 min

Tags:  science-technology  basic-research  broad-institute-of-mit-and-harvard  engineering  pardis-sabeti  plos-biology  viral-genomics

Big step toward identifying all cancer-causing genetic mutations

An international team of 1,300 scientists has generated the most complete cancer genome map to date, bringing researchers closer to identifying all major cancer-causing genetic mutations.

Stephanie McPherson • harvard
Feb. 5, 2020 ~12 min

Tags:  science-technology  basic-research  bioengineering  broad-institute-of-mit-and-harvard  cancer-genome-map  cancer-causing-genetic-mutations  engineering  icgctcga-pan-cancer-analysis-of-whole-genomes-project  pan-cancer-project  whole-cancer-genomes

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