Investigators at Massachusetts General Hospital have modified the gene editing system, making it possible to potentially target any location across the entire human genome.

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.

Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.

Research led by scientists at Harvard and the Broad Institute has optimized the process of making human brain “organoids” — miniature 3D organ models — so they consistently follow growth patterns observed in the developing human brain.

Assistant Professor Brian Liau of the Chemistry and Chemical Biology Department has answered the question of why some new drugs for acute myeloid leukemia don’t work by combining CRISPR gene editing with small-molecule inhibitor treatments in a technique he calls CRISPR-suppressor scanning.

Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.