New test method to detect kidney cancers
A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists.
Tags: cancer health-medicine dana-farber-cancer-institute kidney-cancer biopsy
Scientists produce a reference map of human protein interactions
Scientists produce a reference map of human protein interactions, releasing data helpful for understanding diseases including cancer and infectious diseases such as COVID-19.
Tags: science-technology infectious-diseases cancer covid-19 genes basic-research dana-farber-cancer-institute center-for-cancer-systems-biology human-genome-project human-reference-interactome interactome
Personalized blood biopsies may provide signal of cancer recurrence
Researchers have designed personalized blood biopsies that offer the potential of an early warning signal of breast cancer recurrence.
Tags: science-technology breast-cancer basic-research dana-farber-cancer-institute broad-institute-of-mit-and-harvard blood-biopsies gerstner-center-for-cancer-diagnostics tumor-mutations
Novel drug targets tumor growth in advanced kidney cancer
Harvard researchers at Dana-Farber Cancer Institute have developed a novel targeted drug that shows promise in advanced kidney cancer by interfering with the abnormal blood vessel formation that fuels tumor growth.
Tags: nobel-prize basic-research health-medicine dana-farber-cancer-institute tumors clear-cell-renal-cell-carcinoma hypoxia-inducible-factor kidney-cancer metastatic-disease mk-6482 phase-iii toni-choueiri william-g-kaelin-jr
Study finds racial disparities in culturally competent cancer care
A new study from Harvard-affiliated Dana-Farber Cancer Institute finds that non-white minority survivors are less likely than non-Hispanic whites to be seen by cancer specialists who share or understand their culture.
Tags: health-medicine dana-farber-cancer-institute brandon-a-mahal cancer-specialists hispanic minorities non-white santino-s-butler
High-dose vitamin D shows benefit in patients with advanced colorectal cancer
The first randomized clinical trial of vitamin D in patients with metastatic colorectal cancer found that high doses of supplements combined with chemotherapy delayed disease progression.
Tags: cancer health-medicine dana-farber-cancer-institute vitamin-d delayed-disease-progression metastatic-colorectal-cancer phase-3-trial sunshine-clinical-trial
Harvard study finds cells recall their early development
Study in mice reveals that adult tissues retain a memory of which genes are activated during very early development, and that that memory can be recovered. Under certain conditions, adult cells play their developmental “movie” in a slow rewind, reactivating fetal genes. These findings have important implications for regenerative medicine and cancer research.
Tags: harvard-medical-school health-medicine brigham-and-womens-hospital dana-farber-cancer-institute harvard-stem-cell-institute cell-memory dfci ramesh-shivdasani unmesh-jadhav
Three years after undergoing gene therapy, his ‘last shot’ hit the target
Three years after undergoing gene therapy at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center to treat a life-threatening immune disorder, an Ohio college student is no longer thinking about his own “last shot” for health, but rather about medical school and “giving back.”
Tags: health-medicine alvin-powell becky-whittaker boston-childrens-hospital brenden-whittaker cgd chronic-granulomatous-disease clinical-trial dana-farber-cancer-institute dana-farberboston-childrens-cancer-and-blood-disorders-center david-a-williams gene-therapy
Exercise-related hormone irisin found to target key bone cells
Scientists have discovered that irisin, a hormone released by muscles during exercise, directly acts on key regulatory cells that control the breakdown and formation of bone.
Tags: exercise health-medicine dana-farber-cancer-institute bone-thinning bruce-spiegelman irisin osteocytes osteoporosis
Researchers identify pathway that drives sustained pain following injury
Harvard researchers have identified in mice a set of neurons responsible for sustained pain and pain-coping behaviors. The new study is the first one to map out how these responses arise outside the brain.
Tags: brain harvard-medical-school neurons health-medicine dana-farber-cancer-institute blavatnik-institute-at-harvard-medical-school ekaterina-pesheva pain qiufu-ma signaling-pathways
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