New test method to detect kidney cancers

A novel liquid biopsy method can detect kidney cancers with high accuracy, including small, localized tumors which are often curable but for which no early detection method exists.

Richard Saltus • harvard
June 22, 2020 ~4 min

Tags: cancer health-medicine dana-farber-cancer-institute kidney-cancer biopsy

Scientists produce a reference map of human protein interactions

Scientists produce a reference map of human protein interactions, releasing data helpful for understanding diseases including cancer and infectious diseases such as COVID-19.

Jovana Drinjakovic • harvard
April 8, 2020 ~7 min

Tags:  science-technology  infectious-diseases  cancer  covid-19  genes  basic-research  dana-farber-cancer-institute  center-for-cancer-systems-biology  human-genome-project  human-reference-interactome  interactome

Personalized blood biopsies may provide signal of cancer recurrence

Researchers have designed personalized blood biopsies that offer the potential of an early warning signal of breast cancer recurrence.

Karen Zusi • harvard
March 13, 2020 ~8 min

Tags:  science-technology  breast-cancer  basic-research  dana-farber-cancer-institute  broad-institute-of-mit-and-harvard  blood-biopsies  gerstner-center-for-cancer-diagnostics  tumor-mutations

Novel drug targets tumor growth in advanced kidney cancer

Harvard researchers at Dana-Farber Cancer Institute have developed a novel targeted drug that shows promise in advanced kidney cancer by interfering with the abnormal blood vessel formation that fuels tumor growth.

Richard Saltus • harvard
Feb. 12, 2020 ~4 min

Tags:  nobel-prize  basic-research  health-medicine  dana-farber-cancer-institute  tumors  clear-cell-renal-cell-carcinoma  hypoxia-inducible-factor  kidney-cancer  metastatic-disease  mk-6482  phase-iii  toni-choueiri  william-g-kaelin-jr

Study finds racial disparities in culturally competent cancer care

A new study from Harvard-affiliated Dana-Farber Cancer Institute finds that non-white minority survivors are less likely than non-Hispanic whites to be seen by cancer specialists who share or understand their culture.

Richard Saltus • harvard
Nov. 1, 2019 ~5 min

Tags:  health-medicine  dana-farber-cancer-institute  brandon-a-mahal  cancer-specialists  hispanic  minorities  non-white  santino-s-butler

High-dose vitamin D shows benefit in patients with advanced colorectal cancer

The first randomized clinical trial of vitamin D in patients with metastatic colorectal cancer found that high doses of supplements combined with chemotherapy delayed disease progression.

Richard Saltus • harvard
April 9, 2019 ~6 min

Tags:  cancer  health-medicine  dana-farber-cancer-institute  vitamin-d  delayed-disease-progression  metastatic-colorectal-cancer  phase-3-trial  sunshine-clinical-trial

Harvard study finds cells recall their early development

Study in mice reveals that adult tissues retain a memory of which genes are activated during very early development, and that that memory can be recovered. Under certain conditions, adult cells play their developmental “movie” in a slow rewind, reactivating fetal genes. These findings have important implications for regenerative medicine and cancer research.

Jessica Lau • harvard
March 21, 2019 ~5 min

Tags:  harvard-medical-school  health-medicine  brigham-and-womens-hospital  dana-farber-cancer-institute  harvard-stem-cell-institute  cell-memory  dfci  ramesh-shivdasani  unmesh-jadhav

Three years after undergoing gene therapy, his ‘last shot’ hit the target

Three years after undergoing gene therapy at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center to treat a life-threatening immune disorder, an Ohio college student is no longer thinking about his own “last shot” for health, but rather about medical school and “giving back.”

Alvin Powell • harvard
Feb. 21, 2019 ~17 min

Tags:  health-medicine  alvin-powell  becky-whittaker  boston-childrens-hospital  brenden-whittaker  cgd  chronic-granulomatous-disease  clinical-trial  dana-farber-cancer-institute  dana-farberboston-childrens-cancer-and-blood-disorders-center  david-a-williams  gene-therapy

Exercise-related hormone irisin found to target key bone cells

Scientists have discovered that irisin, a hormone released by muscles during exercise, directly acts on key regulatory cells that control the breakdown and formation of bone.

Richard Saltus • harvard
Dec. 14, 2018 ~5 min

Tags:  exercise  health-medicine  dana-farber-cancer-institute  bone-thinning  bruce-spiegelman  irisin  osteocytes  osteoporosis

Researchers identify pathway that drives sustained pain following injury

Harvard researchers have identified in mice a set of neurons responsible for sustained pain and pain-coping behaviors. The new study is the first one to map out how these responses arise outside the brain.

Ekaterina Pesheva • harvard
Dec. 13, 2018 ~8 min

Tags:  brain  harvard-medical-school  neurons  health-medicine  dana-farber-cancer-institute  blavatnik-institute-at-harvard-medical-school  ekaterina-pesheva  pain  qiufu-ma  signaling-pathways

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