How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy | Feb. 14, 2020 | harvard
~7 mins   

Tags: science-technology base-editing base-editors biotechnology-nature broad-institute caitlin-mcdermott-murphy cas9 chemistry chemistry-and-chemical-biology crispr david-liu dna gene-editing genetic-disease genetic-engineering genome rna sickle-cell-anemia

The story behind the mumps outbreaks of 2016-17

Studying the mumps virus genomes in 2016 and 2017 filled in gaps about how the disease was spreading in Massachusetts and elsewhere in the U.S.

Karen Zusi | Feb. 11, 2020 | harvard
~8 mins   

Tags: science-technology basic-research broad-institute-of-mit-and-harvard engineering pardis-sabeti plos-biology viral-genomics


Big step toward identifying all cancer-causing genetic mutations

An international team of 1,300 scientists has generated the most complete cancer genome map to date, bringing researchers closer to identifying all major cancer-causing genetic mutations.

Stephanie McPherson | Feb. 5, 2020 | harvard
~12 mins   

Tags: science-technology basic-research bioengineering broad-institute-of-mit-and-harvard cancer-genome-map cancer-causing-genetic-mutations engineering icgctcga-pan-cancer-analysis-of-whole-genomes-project pan-cancer-project whole-cancer-genomes

Study likens Earth’s evolution to creation of Frankenstein’s monster

The evolution of the first building blocks on Earth may have been messier than previously thought, likening it to the mishmash creation of Frankenstein’s monster.

Caitlin McDermott-Murphy | Jan. 28, 2020 | harvard
~4 mins   

Tags: science-technology primordial-soup basic-research caitlin-mcdermott-murphy chemistry chemistry-and-chemical-biology dna engineering genetics jack-szostak origins-of-life prebiotic rna science seohyun-kim

Human body-on-chip platform may speed up drug development

Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer alternatives to some animal tests.

Benjamin Boettner | Jan. 27, 2020 | harvard
~15 mins   

Tags: science-technology drug-predictions engineering human-body-on-chip organ-chip science wyss-institute-for-biologically-inspired-engineering

Solid vaccine eliminates acute myeloid leukemia in mice

A new study presents an alternative treatment for acute myeloid leukemia (AML) that has the potential to eliminate AML cells completely.

Lindsay Brownell | Jan. 14, 2020 | harvard
~10 mins   

Tags: health-medicine acute-myeloid-leukemia-aml aml basic-research biomaterial-based-vaccine harvards-wyss-institute-for-biologically-inspired-engineering john-a-paulson-school-of-engineering-and-applied-sciences

A probiotic therapy for patients with inflammatory bowel disease

A genetically programmed living hydrogel material that facilitates intestinal wound healing is being considered for development as a probiotic therapy for patients with inflammatory bowel disease.

Benjamin Boettner | Dec. 6, 2019 | harvard
~7 mins   

Tags: science-technology basic-research crohns-disease e-wyss-institute-for-biologically-inspired-engineering-at-harvard e-coli-nissle-strain ibd inflammatory-bowel-disease mucosal-healing probiotic probiotic-therapy ulcerative-colitis

New laser hits mark on cancer imaging to airport security

Harvard researchers have developed a totally new type of laser that can reach terahertz frequencies offering short-range, high-bandwidth wireless communications, very-high-resolution radar, and spectroscopy.

Leah Burrows | Nov. 15, 2019 | harvard
~7 mins   

Tags: science-technology electromagnetic-spectrum engineering federico-capasso laser physics terahertz-frequencies tunable-terahertz-laser

New drug-detecting tool could help save lives

The landscape of the illegal drug trade changes constantly, particularly amid the current opioid crisis. Law-enforcement officers regularly find or confiscate pills, powders, and other substances and need to know their composition as quickly as possible to determine legal charges and sometimes to issue lifesaving warnings. Carfentanil is a case in point. This cousin to […]

Caitlin McDermott-Murphy | Nov. 13, 2019 | harvard
~7 mins   

Tags: health-medicine basic-research caitlin-mcdermott-murphy cambridge carfentanil chemistry christoffer-abrahamsson dea drug-analysis drug-enforcement-administration engineering-technology fas fentanyl forensic-science george-whitesides law-enforcement opioid-epidemic

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