How CRISPR technology is advancing
Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.
Caitlin McDermott-Murphy | Feb. 14, 2020 | harvard~7 mins
Tags: science-technology base-editing base-editors biotechnology-nature broad-institute caitlin-mcdermott-murphy cas9 chemistry chemistry-and-chemical-biology crispr david-liu dna gene-editing genetic-disease genetic-engineering genome rna sickle-cell-anemia
Radcliffe symposium examines rapid advances brought by CRISPR
CRISPR gene-editing technology has conquered the lab and is poised to lead to new treatments for human disease. Experts consider the promise and peril at Radcliffe.
Alvin Powell | Oct. 28, 2019 | harvard~7 mins
Tags: science-technology alvin-powell crispr gene-editing gene-therapy immaculata-de-vivo jonathan-kimmelman kiran-musunuru radcliffe-institute-for-advanced-study sylvain-moineau vence-bonham
Gene-editing tool prevents hearing loss in mice with hereditary deafness
Scientists have used an optimized version of the CRISPR-Cas9 gene-editing system to prevent hearing loss in so-called Beethoven mice, which carry a genetic mutation that causes profound hearing loss in humans and mice alike.
Ekaterina Pesheva | July 3, 2019 | harvard~12 mins
Tags: science-technology beethoven-mice blavatnik-institute-at-harvard-medical-school deafness gene-editing-tool hearing-loss
Breakthrough Harvard research shows stem cell genes can be edited in living systems
Study shows how genes could be edited in stem cells within intact organs, without having to remove them from their normal environment. The new approach could treat a variety of diseases.
Mary Todd Bergman | June 4, 2019 | harvard~6 mins
Tags: science-technology amy-wagers gene-editing jill-goldstein sharif-tabebordbar ya-chieh-hsu
Brigham, Broad Institute researchers ID molecules that rein in CRISPR systems
Scientists have identified the first chemical compounds able to inhibit and regulate CRISPR systems, which could ultimately make CRISPR gene-editing technologies more precise, efficient, and safe.
Karen Zusi | May 2, 2019 | harvard~5 mins
Tags: science-technology amit-choudhary brigham-and-womens-hospital broad-institute cas-enzymes cell crispr gene-editing
Harvard researchers share views on future, ethics of gene editing
Harvard researchers and others share their views on the issues involved in gene editing.
Mary Todd Bergman | Jan. 9, 2019 | harvard~22 mins
Tags: health-medicine science-technology feng-zhang gene-editing george-church george-q-daley he-jiankui i-glenn-cohen kevin-eggan mary-todd-bergman richard-hamermesh robert-truog sheila-jasanoff
Harvard researchers share views on future, ethics of gene editing
Harvard researchers and others share their views on the issues involved in gene editing.
Mary Todd Bergman | Jan. 9, 2019 | harvard~22 mins
Tags: health-medicine science-technology feng-zhang gene-editing george-church george-q-daley he-jiankui i-glenn-cohen kevin-eggan mary-todd-bergman richard-hamermesh robert-truog sheila-jasanoff
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