The evolution of the first building blocks on Earth may have been messier than previously thought, likening it to the mishmash creation of Frankenstein’s monster.

In a paper published in PNAS, Jack W. Szostak, professor of chemistry and chemical biology at Harvard, along with graduate student Seohyun (Chris) Kim, suggest that RNA could have started with a different set of nucleotide bases. In place of guanine, RNA could have relied on a surrogate, inosine.

In a paper published in PNAS, Jack W. Szostak, professor of chemistry and chemical biology at Harvard, along with graduate student Seohyun (Chris) Kim, suggest that RNA could have started with a different set of nucleotide bases. In place of guanine, RNA could have relied on a surrogate, inosine.