Harvard Professor Arthur Kleinman’s wife, Joan, began to struggle with a rare form of early Alzheimer’s disease at 59. Eight years after losing her, he chronicles their journey in “The Soul of Care: The Moral Education of a Husband and a Doctor.”

The Gazette spoke with History of Science Professor Anne Harrington about her new book, “Mind Fixers: Psychiatry’s Troubled Search for the Biology of Mental Illness,” which traces the treatment of mental disorders from its early years to the Prozac Nation of today.