Progeria study finds base-editing therapy lengthens lifespan in mice

Several hundred children worldwide live with progeria, a deadly premature aging disease.

Caitlin McDermott-Murphy • harvard
Jan. 27, 2021 ~9 min

Analyzing toehold sequences for synthetic biology

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications.

Lindsay Brownell • harvard
Oct. 7, 2020 ~16 min


Gene editing may be a path to restore partial hearing

Wei Hsi “Ariel” Yeh dedicated her research in chemistry to solving some of the vast genetic mysteries behind hearing loss.

Caitlin McDermott-Murphy • harvard
June 5, 2020 ~6 min

How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy • harvard
Feb. 14, 2020 ~7 min

Study likens Earth’s evolution to creation of Frankenstein’s monster

The evolution of the first building blocks on Earth may have been messier than previously thought, likening it to the mishmash creation of Frankenstein’s monster.

Caitlin McDermott-Murphy • harvard
Jan. 28, 2020 ~4 min

Researchers can program a CRISPR enzyme to kill viruses in human cells

Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Karen Zusi • harvard
Oct. 10, 2019 ~5 min

Inosine could be a potential route to the first RNA, Harvard study says

In a paper published in PNAS, Jack W. Szostak, professor of chemistry and chemical biology at Harvard, along with graduate student Seohyun (Chris) Kim, suggest that RNA could have started with a different set of nucleotide bases. In place of guanine, RNA could have relied on a surrogate, inosine.

Caitlin McDermott-Murphy • harvard
Dec. 10, 2018 ~4 min

Inosine could be a potential route to the first RNA, Harvard study says

In a paper published in PNAS, Jack W. Szostak, professor of chemistry and chemical biology at Harvard, along with graduate student Seohyun (Chris) Kim, suggest that RNA could have started with a different set of nucleotide bases. In place of guanine, RNA could have relied on a surrogate, inosine.

Caitlin McDermott-Murphy • harvard
Dec. 10, 2018 ~4 min


/

1