How CRISPR technology is advancing

Fewer off-target edits and greater targeting scope bring gene editing technology closer to treating human diseases.

Caitlin McDermott-Murphy | Feb. 14, 2020 | harvard
~7 mins   

Tags: science-technology base-editing base-editors biotechnology-nature broad-institute caitlin-mcdermott-murphy cas9 chemistry chemistry-and-chemical-biology crispr david-liu dna gene-editing genetic-disease genetic-engineering genome rna sickle-cell-anemia

Study likens Earth’s evolution to creation of Frankenstein’s monster

The evolution of the first building blocks on Earth may have been messier than previously thought, likening it to the mishmash creation of Frankenstein’s monster.

Caitlin McDermott-Murphy | Jan. 28, 2020 | harvard
~4 mins   

Tags: science-technology primordial-soup basic-research caitlin-mcdermott-murphy chemistry chemistry-and-chemical-biology dna engineering genetics jack-szostak origins-of-life prebiotic rna science seohyun-kim

Largest gaseous structure ever seen in our galaxy is discovered

Astronomers at Harvard have discovered a monolithic, wave-shaped gaseous structure — the largest ever seen in our galaxy — and dubbed it the “Radcliffe Wave."

Mary Todd Bergman | Jan. 7, 2020 | harvard
~9 mins   

Tags: science-technology goulds-belt alyssa-goodman astrophysical-journal milky-way-galaxy physics radcliffe-institute-for-advanced-study radcliffe-wave worldwide-telescope

Researchers can program a CRISPR enzyme to kill viruses in human cells

Researchers have turned a CRISPR enzyme into an antiviral that can be programmed to detect and destroy RNA-based viruses in human cells.

Karen Zusi | Oct. 10, 2019 | harvard
~5 mins   

Tags: science-technology broad-institute-of-mit-and-harvard carver cas13-enzyme cas13-assisted-restriction-of-viral-expression-and-readout crispr ebola flu rna rna-based-viruses sherlock virus zika

Urgency of climate change may be understated in intergovernmental panel report

The world’s oceans, glaciers, and ice caps are under assault by climate change. The Gazette spoke with former Obama science adviser John Holdren about the latest Intergovernmental Panel on Climate Change report examining the threat.

Alvin Powell | Oct. 2, 2019 | harvard
~14 mins   

Tags: science-technology wildfire alvin-powell arctic-initiative belfer-center-for-science-and-international-affairs climate-change global-warming harvard-kennedy-school heat-wave intergovernmental-panel-on-climate-change john-holdren permafrost public-opinion sea-level-rise

Major study finds omega-3 supplements may reduce risk of heart attack

Harvard study finds that greater cardiovascular benefits may be achieved at higher doses of omega-3 fish oil supplementation.

Amy Roeder | Sept. 30, 2019 | harvard
~4 mins   

Tags: health-medicine brigham-and-womens-hospital cardiovascular-disease harvard-th-chan-school-of-public-health heart-attacks journal-of-the-american-heart-association omega-3-fish-oil-supplements vital-trial

Plant-based diet may lower risk of Type 2 diabetes

A new meta-analysis shows that people who follow predominantly plant-based diets with greater adherence have a 23 percent lower risk of developing Type 2 diabetes than those who follow these diets with lower adherence.

Amy Roeder | July 22, 2019 | harvard
~3 mins   

Tags: health-medicine harvard-th-chan-school-of-public-health jama-internal-medicine plant-based-diet type-2-diabetes

Theory that ridged skin helps dolphins debunked

New study debunks long-held theory that dolphins had ridged skin, which helped them swim faster.

Clea Simon | July 18, 2019 | harvard
~6 mins   

Tags: science-technology clea-simon dolphin-skin fas george-lauder marine-mammal oeb organismic-and-evolutionary-biology royal-society-biology-letters-journal

Carrot-and-stick system appears to slow growth of health costs

Study led by Harvard researchers finds that a long-term trial of a capped-payment system encouraged preventative care and discouraged unnecessary spending

Jake Miller | July 15, 2019 | harvard
~7 mins   

Tags: health-medicine blavatnik-institute department-of-health-care-policy harvard-medical-school insurance jake-miller the-new-england-journal-of-medicine

Trial shows antihypertension drug may improve pancreatic cancer outcomes

Adding the blood-pressure drug losartan to the intensive chemo and radiation protocol for treating locally advanced pancreatic cancer allowed complete removal of the tumor in 61 percent of trial participants and significantly improved survival rates.

Sue McGreevey | May 30, 2019 | harvard
~5 mins   

Tags: health-medicine blood-pressure carlos-fernandez-del-castillo janet-murphy jennifer-wo losartan massachusetts-general-hospital mgh pancreatic-cancer rakesh-k-jain theodore-hang

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