New technique could treat cancer metastasis

Delivering immune-stimulating nanoparticles to the lungs via red blood cells halts tumor growth in mice.

Lindsay Brownell • harvard
Nov. 16, 2020 ~10 min

cancer seas health-medicine wyss-institute lindsay-brownell john-a-paulson-school-for-engineering-and-applied-sciences

Enzymatic DNA synthesis sees the light

Controlling a DNA-synthesizing enzyme with photolithographic methods from the computer chip industry facilitates multiplexed writing and storage of digital data in DNA.

Benjamin Boettner • harvard
Oct. 19, 2020 ~9 min

science-technology dna harvard-medical-school george-church wyss-institute

Analyzing toehold sequences for synthetic biology

Computational algorithms enable identification and optimization of RNA-based tools for myriad applications.

Lindsay Brownell • harvard
Oct. 7, 2020 ~16 min

science-technology dna synthetic-biology rna wyss-institute james-collins

Vaccine strategy could aid in COVID-19 immunization

A biomaterials-based infection vaccine strategy shows first promise in eliciting immunity against SARS-CoV-2 and could be applied broadly to stave off infectious disease.

Benjamin Boettner • harvard
Aug. 19, 2020 ~8 min

science-technology covid-19 coronavirus david-mooney wyss-institute vaccine omnivax

Wyss Institute’s improved face shield design hits 7M mark

The Wyss Institute made improvements to its face shields based on recommendations from area hospitals. Joining forces with a Mansfield, Mass.-based manufacturer, the institute’s face shields are now being produced at a rate of 400,000 a day.

Lindsay Brownell • harvard
Aug. 17, 2020 ~11 min

science-technology covid-19 wyss-institute inc ppe jennifer-lewis lacerta-group

Red blood cells could generate immune response via vaccines

New platform technology uses red blood cells to generate targeted immune responses in mice

Lindsay Brownell • harvard
July 13, 2020 ~8 min

science-technology john-a-paulson-school-of-engineering-and-applied-sciences seas donald-ingber samir-mitragotri wyss-institute vaccines anvay-ukidve vaccinations

Wyss researchers predict biggest scientific advances of 2020s

The Wyss Institute asked its faculty members to predict the biggest scientific advancements in their fields in the next 10 years.

Lindsay Brownell • harvard
Jan. 13, 2020 ~10 min

 science-technology  wyss-institute  2030  predictions  scientific-advances

Lab-grown meat gains muscle as it moves from petri dish to dinner plate

Researchers are able to build muscle fibers, giving lab-grown meat the texture meat lovers seek.

Leah Burrows • harvard
Oct. 21, 2019 ~7 min

 science-technology  harvard-john-a-paulson-school-of-engineering-and-applied-sciences  wyss-institute  lab-grown-meat  kit-parker  muscle-tissues

Creating a reliable clock to track changes in microbiome

The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging, especially when attempting to study it in living subjects. A new genetic “repressilator” lets scientists noninvasively study its dynamics, acting like a clock that tracks how bacterial growth changes over time with single-cell precision.

Lindsay Brownell • harvard
Oct. 11, 2019 ~9 min

 science-technology  harvard-medical-school  wyss-institute  microbiome  bacterial-growth  repressilator

Wyss Institute develops technology to better study blood-brain barrier

Wyss Institute scientists have developed chip technology that mimics the blood-brain barrier in humans. The new models will help researchers study drugs to treat cancer, neurodegeneration, and other diseases of the central nervous system.

Benjamin Boettner • harvard
June 21, 2019 ~11 min

 science-technology  donald-ingber  organ-chips  wyss-institute  organs-on-chips  blood-brain-barrier  eric-shusta  james-gorman  nur-mustafaoglu  tae-eun-park