Human body-on-chip platform may speed up drug development

Multiple human organ chips that quantitatively predict drug pharmacokinetics may offer alternatives to some animal tests.

Benjamin Boettner | Jan. 27, 2020 | harvard
~15 mins   

Tags: science-technology drug-predictions engineering human-body-on-chip organ-chip science wyss-institute-for-biologically-inspired-engineering

Solid vaccine eliminates acute myeloid leukemia in mice

A new study presents an alternative treatment for acute myeloid leukemia (AML) that has the potential to eliminate AML cells completely.

Lindsay Brownell | Jan. 14, 2020 | harvard
~10 mins   

Tags: health-medicine acute-myeloid-leukemia-aml aml basic-research biomaterial-based-vaccine harvards-wyss-institute-for-biologically-inspired-engineering john-a-paulson-school-of-engineering-and-applied-sciences

Wyss researchers predict biggest scientific advances of 2020s

The Wyss Institute asked its faculty members to predict the biggest scientific advancements in their fields in the next 10 years.

Lindsay Brownell | Jan. 13, 2020 | harvard
~10 mins   

Tags: science-technology 2030 predictions scientific-advances wyss-institute

A probiotic therapy for patients with inflammatory bowel disease

A genetically programmed living hydrogel material that facilitates intestinal wound healing is being considered for development as a probiotic therapy for patients with inflammatory bowel disease.

Benjamin Boettner | Dec. 6, 2019 | harvard
~7 mins   

Tags: science-technology basic-research crohns-disease e-wyss-institute-for-biologically-inspired-engineering-at-harvard e-coli-nissle-strain ibd inflammatory-bowel-disease mucosal-healing probiotic probiotic-therapy ulcerative-colitis

Better delivery system for sending chemo to cancerous lung tissue

A new technique called ELeCt (erythrocyte-leveraged chemotherapy) can transport drug-loaded nanoparticles into cancerous lung tissue by mounting them on the body’s own red blood cells.

Lindsay Brownell | Nov. 13, 2019 | harvard
~8 mins   

Tags: science-technology basic-research biodegradable-polymer cancer chemotherapy elect engineering erythrocyte-leveraged-chemotherapy john-a-paulson-school-of-engineering-and-applied-sciences lung-cancer trojan-horse wyss-institute-for-biologically-inspired-engineering

New blood test could be used to help millions infected with TB

A team of researchers has developed a point-of-care TB test that costs only $2 and gives results in about 30 minutes, lowering the barrier to care in low-resource settings and potentially saving millions of lives.

Lindsay Brownell | Oct. 23, 2019 | harvard
~9 mins   

Tags: health-medicine active-tuberculosis atb brigham-and-womens-hospital broad-institute-of-harvard-and-mit tb tb-triage-test wyss-institute-for-biologically-inspired-engineering

Lab-grown meat gains muscle as it moves from petri dish to dinner plate

Researchers are able to build muscle fibers, giving lab-grown meat the texture meat lovers seek.

Leah Burrows | Oct. 21, 2019 | harvard
~7 mins   

Tags: science-technology harvard-john-a-paulson-school-of-engineering-and-applied-sciences kit-parker lab-grown-meat muscle-tissues wyss-institute

Creating a reliable clock to track changes in microbiome

The microbiome is a treasure trove of information about human health and disease, but getting it to reveal its secrets is challenging, especially when attempting to study it in living subjects. A new genetic “repressilator” lets scientists noninvasively study its dynamics, acting like a clock that tracks how bacterial growth changes over time with single-cell precision.

Lindsay Brownell | Oct. 11, 2019 | harvard
~9 mins   

Tags: science-technology bacterial-growth harvard-medical-school microbiome repressilator wyss-institute

Shape-shifting structures can take the form of a face, antenna

What would it take to transform a flat sheet into a human face? How would the sheet need to grow and shrink to form eyes that are concave, a nose that’s convex, and a chin that protrudes? How to encode and release complex curves in shape-shifting structures is at the center of research led by […]

Leah Burrows | Oct. 2, 2019 | harvard
~6 mins   

Tags: science-technology harvard-john-a-paulson-school-of-engineering-and-applied-sciences harvard-wyss-institute-of-biologically-inspired-engineering multi-scale-curvature shape-shifting

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