K. Lisa Yang Brain-Body Center to investigate the brain’s complex relationship with other body systems.

This circuit, which weakens with age, could offer a target to help prevent age-related decline in spatial memory.

Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

MIT biologists show that enlargement of blood stem cells restricts their ability to generate new blood cells during aging.

The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia.

Analysis of Medicare data finds location matters, not just past health behavior.

To quickly express learning and memory genes, brain cells snap both strands of DNA in many more places and cell types than previously realized, a new study shows.

Research on mice suggests aging affects a brain circuit critical for learning to make some types of decisions.

Center will work with affiliated researchers to test low-cost, high-impact behavioral interventions to improve health-care delivery and health outcomes for aging adults in the United States.

Reactivating an enzyme that promotes DNA repair can help to reverse age-related cognitive decline in mice.