Chemical synthesis yields potential antibiotic

A new strategy for producing a natural compound could also be used to generate variants with even stronger antimicrobial activity.

Anne Trafton | MIT News Office • mit
Feb. 24, 2022 ~6 min

Protein structure offers clues to drug-resistance mechanism

A new study sheds light on how a protein pumps toxic molecules out of bacterial cells.

Anne Trafton | MIT News Office • mit
Feb. 18, 2022 ~6 min


Metabolic mutations help bacteria resist drug treatment

Study suggests forcing bacteria to burn more energy could make them more susceptible to antibiotics.

Anne Trafton | MIT News Office • mit
Feb. 18, 2021 ~7 min

SMART researchers use lysins to selectively target bacteria

The discovery can help to cure bacterial infections without inducing resistance or causing harm to good bacteria.

Singapore-MIT Alliance for Research and Technology • mit
Dec. 10, 2020 ~6 min

Algorithm reduces use of riskier antibiotics for UTIs

Machine learning model predicts probability that a particular urinary tract infection can be treated by specific antibiotics.

Adam Conner-Simons | Rachel Gordon | MIT CSAIL • mit
Nov. 5, 2020 ~7 min

Making tuberculosis more susceptible to antibiotics

Shortening carbohydrates in the bacterial cell wall makes them more vulnerable to certain drugs.

Anne Trafton | MIT News Office • mit
Sept. 16, 2020 ~6 min

A new way to make bacteria more sensitive to antibiotics

SMART researchers find exposing bacteria to hydrogen sulfide can increase antimicrobial sensitivity in bacteria that do not produce H2S.

Singapore-MIT Alliance for Research and Technology • mit
Sept. 3, 2020 ~4 min

How often do vaccine trials hit paydirt?

Study: Vaccines find more success in development than any other kind of drug, but have been relatively neglected in recent decades.

Peter Dizikes | MIT News Office • mit
May 27, 2020 ~8 min


SMART researchers uncover new anti-phage defense mechanisms

Discovery explains why some bacteria have been able to defend against phage therapy, opens new ways to overcome existing challenges.

Singapore-MIT Alliance for Research and Technology • mit
May 13, 2020 ~5 min

SMART announces new method for processing fluid droplets

Microfluidics enables researchers to create unique environment for developing medicine, paving the way for more potent, high-quality drugs.

Singapore-MIT Alliance for Research and Technology • mit
March 16, 2020 ~5 min

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