New gene regulation model provides insight into brain development

A well-known protein family binds to many more RNA sequences than previously thought in order to help neurons grow.

Raleigh McElvery | Department of Biology • mit
Sept. 8, 2020 ~7 min

Tags: genetics neuroscience development biology data research school-of-science computer-modeling

Scientists discover new rules about “runaway” transcription

Findings related to bacterial gene expression overturn fundamental assumptions about basic biological pathways.

Raleigh McElvery | Department of Biology • mit
Sept. 2, 2020 ~7 min

Tags: dna physics genetics bacteria biology rna research school-of-science

Study suggests animals think probabilistically to distinguish contexts

New statistical model may help scientists understand how animals infer whether surroundings are novel or haven’t changed enough to be a new context.

David Orenstein | Picower Institute for Learning and Memory • mit
Aug. 12, 2020 ~6 min

Tags: biology memory research behavior school-of-science brain-and-cognitive-sciences center-for-brains-minds-and-machines picower-institute

SMART research enhances dengue vaccination in mice

Sequential immunization might be safer and more effective than the existing tetravalent vaccine.

Singapore-MIT Alliance for Research and Technology • mit
Aug. 11, 2020 ~5 min

Tags: health biology vaccines disease viruses research school-of-science singapore-mit-alliance-for-research-and-technology-smart

Bringing RNA into genomics

ENCODE consortium identifies RNA sequences that are involved in regulating gene expression.

Anne Trafton | MIT News Office • mit
July 29, 2020 ~7 min

Tags: genetics biology rna research school-of-science

Gene-controlling mechanisms play key role in cancer progression

Study finds “epigenomic” alterations evolve as lung tumors become more aggressive and metastasize.

Anne Trafton | MIT News Office • mit
July 23, 2020 ~7 min

Tags: dna cancer biology research school-of-science national-institutes-of-health-nih koch-institute

3 Questions: Ibrahim Cissé on using physics to decipher biology

A biophysicist employs super-resolution microscopy to peer inside living cells and witness never-before-seen phenomena.

Raleigh McElvery | Department of Biology • mit
July 22, 2020 ~7 min

Tags: dna physics biology research school-of-science faculty 3-questions

Flatworms muscle new eyes' wiring into their brains

Peter Reddien's lab at the Whitehead Institute takes a step forward in understanding how neural circuits could be regenerated in adults.

Eva Frederick | Whitehead Institute • mit
July 8, 2020 ~8 min

Tags: neuroscience development biology animals research school-of-science whitehead-institute

How cancer drugs find their targets

Certain cancer therapeutics concentrate within cells — a finding that could change the way scientists think about drug design.

Eva Frederick | Whitehead Institute • mit
June 26, 2020 ~10 min

Tags: medicine cancer biology research drug-development school-of-science whitehead-institute koch-institute drug-delivery

Like a treasure map, brain region emphasizes reward location

The lateral septum encodes spatial information with a special emphasis on where the reward lies.

David Orenstein | Picower Institute for Learning and Memory • mit
June 23, 2020 ~4 min

Tags: neuroscience biology memory learning research school-of-science brain-and-cognitive-sciences picower-institute

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