An “oracle” for predicting the evolution of gene regulation
Researchers create a mathematical framework to examine the genome and detect signatures of natural selection, deciphering the evolutionary past and future of non-coding DNA.
Raleigh McElvery | Department of Biology •
mit
March 11, 2022 • ~9 min
March 11, 2022 • ~9 min
In Down syndrome cells, genome-wide disruptions mimic a senescence-like state
Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.
David Orenstein | Picower Institute •
mit
Jan. 10, 2022 • ~7 min
Jan. 10, 2022 • ~7 min
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