Study shows fragile X treatment can incur resistance, suggests ways around it
While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental-critical period.
David Orenstein | Picower Institute for Learning and Memory •
mit
Oct. 15, 2021 • ~10 min
Oct. 15, 2021 • ~10 min
Behind the scenes, brain circuit ensures vision remains reliable
A study of mice watching movies shows our brain cells rely on a circuit of inhibitory neurons to help ensure that the same images are represented consistently.
David Orenstein | Picower Institute for Learning and Memory •
mit
Sept. 27, 2021 • ~7 min
Sept. 27, 2021 • ~7 min
Novel approach reverses amblyopia in animals
By temporarily suspending retinal activity in the non-amblyopic eye of animal models, neuroscientists restrengthen the visual response in the "lazy" eye, even at ages after the critical period when patch therapy fails.
David Orenstein | Picower Institute for Learning and Memory •
mit
Sept. 20, 2021 • ~6 min
Sept. 20, 2021 • ~6 min
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