Study suggests new molecular strategy for treating fragile X syndrome

Enhancing activity of a specific component of neurons’ “NMDA” receptors normalized protein synthesis, neural activity, and seizure susceptibility in the hippocampus of fragile X lab mice.

David Orenstein | The Picower Institute for Learning and Memory • mit
March 4, 2025 ~7 min

Seeing more in expansion microscopy

New methods light up lipid membranes and let researchers see sets of proteins inside cells with high resolution.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
March 3, 2025 ~10 min


An ancient RNA-guided system could simplify delivery of gene editing therapies

The programmable proteins are compact, modular, and can be directed to modify DNA in human cells.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Feb. 27, 2025 ~7 min

Study: Even after learning the right idea, humans and animals still seem to test other approaches

New research adds evidence that learning a successful strategy for approaching a task doesn’t prevent further exploration, even if doing so reduces performance.

David Orenstein | The Picower Institute for Learning and Memory • mit
Feb. 21, 2025 ~6 min

MIT method enables ultrafast protein labeling of tens of millions of densely packed cells

Tissue processing advance can label proteins at the level of individual cells across large samples just as fast and uniformly as in dissociated single cells.

David Orenstein | The Picower Institute for Learning and Memory • mit
Feb. 6, 2025 ~9 min

How one brain circuit encodes memories of both places and events

A new computational model explains how neurons linked to spatial navigation can also help store episodic memories.

Anne Trafton | MIT News • mit
Jan. 15, 2025 ~9 min

For healthy hearing, timing matters

Machine-learning models let neuroscientists study the impact of auditory processing on real-world hearing.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Jan. 14, 2025 ~7 min

Study suggests how the brain, with sleep, learns meaningful maps of spaces

Place cells are known to encode individual locations, but research finds stitching together a “cognitive map” of a whole environment requires a broader ensemble of cells, aided by sleep, over several days.

David Orenstein | The Picower Institute for Learning and Memory • mit
Jan. 10, 2025 ~8 min


Teaching AI to communicate sounds like humans do

Inspired by the mechanics of the human vocal tract, a new AI model can produce and understand vocal imitations of everyday sounds. The method could help build new sonic interfaces for entertainment and education.

Alex Shipps | MIT CSAIL • mit
Jan. 9, 2025 ~8 min

Personal interests can influence how children’s brains respond to language

McGovern Institute neuroscientists use children’s interests to probe language in the brain.

Rubina Veerakone | McGovern Institute for Brain Research • mit
Jan. 7, 2025 ~6 min

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