Matthew Vander Heiden seeks new cancer treatments that exploit tumor cells’ abnormal metabolism.

Whitehead team deploys CRISPR tools to better understand and uncover ways of improving methotrexate, a popular chemotherapy drug.

Researchers identify the amino acid aspartate as a metabolic limitation in certain cancers.

Mechanism-based cancer prevention is poised to further decrease the numbers of U.S. cancer deaths, says MIT professor emerita.

Shortfall of digestive enzymes can lead to tissue breakdown in early stages of pancreatic cancer.

Nanoparticles carrying two drugs can cross the blood-brain barrier and shrink glioblastoma tumors.

A drug treatment that mimics fasting can also provide the same benefit, study finds.