Atlas of human brain blood vessels highlights changes in Alzheimer’s disease

MIT researchers characterize gene expression patterns for 22,500 brain vascular cells across 428 donors, revealing insights for Alzheimer’s onset and potential treatments.

Rachel Gordon | MIT CSAIL • mit
June 21, 2023 ~17 min

Gene-editing technique could speed up study of cancer mutations

With the new method, scientists can explore many cancer mutations whose roles are unknown, helping them develop new drugs that target those mutations.

Anne Trafton | MIT News Office • mit
May 11, 2023 ~9 min


An unprecedented view of gene regulation

MIT engineers’ new technique analyzes the 3D organization of the genome at a resolution 100 times higher than before.

Anne Trafton | MIT News Office • mit
May 8, 2023 ~10 min

Researchers map brain cell changes in Alzheimer’s disease

Study reveals key cell structures and gene expression changes near amyloid plaques and tau tangles in mouse brain tissue.

Allessandra DiCorato | Broad Institute • mit
Feb. 2, 2023 ~7 min

New technologies reveal cross-cutting breakdowns in Alzheimer’s disease

“Single-cell profiling” is helping neuroscientists see how disease affects major brain cell types and identify common, potentially targetable pathways.

David Orenstein | Picower Institute for Learning and Memory • mit
Jan. 18, 2023 ~6 min

Scientists discover a new way of sharing genetic information in a common ocean microbe

Prochlorococcus, the world’s most abundant photosynthetic organism, reveals a gene-transfer mechanism that may be key to its abundance and diversity.

David L. Chandler | MIT News Office • mit
Jan. 5, 2023 ~8 min

New CRISPR-based tool inserts large DNA sequences at desired sites in cells

Known as PASTE, the technique holds potential for treating a variety of diseases caused by faulty genes.

Anne Trafton | MIT News Office • mit
Nov. 24, 2022 ~8 min

Scientists unveil the functional landscape of essential genes

Researchers harness new pooled, image-based screening method to probe the functions of over 5,000 essential genes in human cells.

Nicole Davis | Whitehead Institute • mit
Nov. 21, 2022 ~6 min


An interdisciplinary journey through living machines

With NEET, Sherry Nyeo is discovering MIT’s undergraduate research community at the intersection of computer science and biological engineering.

Jiyoo Jye | New Engineering Education Transformation (NEET) program • mit
Oct. 18, 2022 ~5 min

With fractured genomes, Alzheimer’s neurons call for help

Study indicates ailing neurons may instigate an inflammatory response from the brain’s microglia immune cells.

David Orenstein | Picower Institute for Learning and Memory • mit
Oct. 4, 2022 ~8 min

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