Using gene editing, neuroscientists develop a new model for autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Anne Trafton | MIT News Office • mit
June 12, 2019 ~9 min

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

Karen Zusi | Broad Institute • mit
June 12, 2019 ~7 min


Scientists engineer new CRISPR platform for DNA targeting

CRISPR team harnesses new Cas12b enzyme for use in eukaryotic cells, adding to the CRISPR toolbox.

Broad Institute • mit
Jan. 22, 2019 ~4 min

New CRISPR tool opens up more of the genome for editing

Enzyme can target almost half of the genome’s “ZIP codes” and could enable editing of many more disease-specific mutations.

Helen Knight | MIT News correspondent • mit
Oct. 24, 2018 ~6 min

Researchers advance CRISPR-based tool for diagnosing disease | MIT News

With SHERLOCK, a strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest.

Broad Institute • mit
Feb. 15, 2018 ~6 min

Reading and writing DNA | MIT News

Department of Biology kicks off IAP seminar series with a lecture by synthetic-biology visionary George Church.

Raleigh McElvery | Department of Biology • mit
Jan. 31, 2018 ~8 min

Researchers engineer CRISPR to edit single RNA letters in human cells | MIT News

“REPAIR” system edits RNA, rather than DNA; has potential to treat diseases without permanently affecting the genome.

Broad Institute • mit
Oct. 25, 2017 ~6 min

Gene-editing technology developer Feng Zhang awarded $500,000 Lemelson-MIT Prize | MIT News

MIT associate professor and member of the Broad Institute and McGovern Institute recognized for commitment to invention, collaboration, and mentorship.

Lemelson-MIT Program • mit
Sept. 19, 2017 ~5 min


Feng Zhang to share Albany Medical Prize | MIT News

Five recipients honored for their fundamental and complementary accomplishments related to CRISPR-Cas9.

McGovern Institute for Brain Research • mit
Aug. 15, 2017 ~2 min

Scientists unveil CRISPR-based diagnostic platform | MIT News

New system adapts tool known for gene editing; to be used in rapid, inexpensive disease diagnosis.

Broad Institute • mit
April 13, 2017 ~7 min

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