Finding the brain’s compass

A powerful method has allowed McGovern researchers to discover how the brain represents the complex world in simple shapes.

Sabbi Lall | McGovern Institute for Brain Research • mit
Aug. 12, 2019 ~6 min

Tags: neuroscience research school-of-science brain-and-cognitive-sciences mcgovern-institute

Neuroscientists identify brain region linked to altered social interactions in autism model

In a mouse model, restoring activity of a specific forebrain region reverses social traits associated with autism.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 26, 2019 ~4 min

Tags: genetics neuroscience autism broad-institute research school-of-science brain-and-cognitive-sciences mcgovern-institute

How expectation influences perception

Neuroscientists find brain activity patterns that encode our beliefs and affect how we interpret the world around us.

Anne Trafton | MIT News Office • mit
July 15, 2019 ~8 min

Tags: neuroscience memory research school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

New CRISPR platform expands RNA editing capabilities

The new system, dubbed RESCUE, allows RNA edits to be made that were not previously possible.

Sabbi Lall | McGovern Institute for Brain Research • mit
July 11, 2019 ~6 min

Tags: dna genetics crispr rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute


A chemical approach to imaging cells from the inside

Researchers develop a new microscopy system for creating maps of cells, using chemical reactions to encode spatial information.

Karen Zusi | Broad Institute • mit
June 20, 2019 ~4 min

Tags: dna imaging microscopy rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute

Using gene editing, neuroscientists develop a new model for autism

By introducing a gene variant associated with autism into monkeys, researchers hope to study treatment options for severe neurodevelopmental disorders.

Anne Trafton | MIT News Office • mit
June 12, 2019 ~9 min

Tags: crispr neuroscience autism china broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences mcgovern-institute genome-editing

New gene-editing system precisely inserts large DNA sequences into cellular DNA

Researchers identify and develop new CRISPR-associated transposase system for targeted integration of DNA, adding key capabilities to gene-editing technology.

Karen Zusi | Broad Institute • mit
June 12, 2019 ~7 min

Tags: dna genetics crispr rna broad-institute research school-of-engineering school-of-science brain-and-cognitive-sciences biological-engineering mcgovern-institute genome-editing

Neurons’ “antennae” are unexpectedly active in neural computation

Tiny, branching extensions called dendrites may be more than just passive information-carriers, study finds.

Anne Trafton | MIT News Office • mit
June 6, 2019 ~6 min

Tags: neuroscience research cells school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih mcgovern-institute

How we make complex decisions

Neuroscientists identify a brain circuit that helps break decisions down into smaller pieces.

Anne Trafton | MIT News Office • mit
May 16, 2019 ~8 min

Tags: neuroscience research behavior school-of-science brain-and-cognitive-sciences mcgovern-institute

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