“Traveling” nature of brain waves may help working memory work

The act of holding information in mind is accompanied by coordination of rotating brain waves in the prefrontal cortex, a phenomenon that may convey specific advantages, a new study suggests.

David Orenstein | Picower Institute for Learning and Memory • mit
Feb. 10, 2022 ~7 min

Where did that sound come from?

MIT neuroscientists have developed a computer model that can answer that question as well as the human brain.

Anne Trafton | MIT News Office • mit
Jan. 27, 2022 ~8 min


In Down syndrome cells, genome-wide disruptions mimic a senescence-like state

Extra chromosome alters chromosomal conformation and DNA accessibility in neural progenitor cells, disrupting gene transcription and cell functions much like in cellular aging.

David Orenstein | Picower Institute • mit
Jan. 10, 2022 ~7 min

Perfecting pitch perception

Computational modeling shows that both our ears and our environment influence how we hear.

Jennifer Michalowski | McGovern Institute for Brain Research • mit
Dec. 17, 2021 ~6 min

Research finds potential mechanism linking autism, intestinal inflammation

Infection during pregnancy with elevated levels of the cytokine IL-17a may yield microbiome alterations that prime offspring for aberrant immune responses, mouse study suggests.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 9, 2021 ~8 min

Study reveals a protein’s key contribution to heterogeneity of neurons

Tomosyn’s tight regulation of neurotransmitter release distinguishes functions of two neuron classes at the fly neuromuscular junction.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 7, 2021 ~7 min

Feast or forage? Study finds circuit that helps a brain decide

By integrating multiple sensory inputs, a loop of mutual inhibition among a small set of neurons allows worms to switch between long-lasting behavioral states.

David Orenstein | Picower Institute for Learning and Memory • mit
Dec. 6, 2021 ~7 min

Study finds a striking difference between neurons of humans and other mammals

Human neurons have fewer ion channels, which might have allowed the human brain to divert energy to other neural processes.

Anne Trafton | MIT News Office • mit
Nov. 10, 2021 ~8 min


Study links gene to cognitive resilience in the elderly

The findings may help explain why some people who lead enriching lives are less prone to Alzheimer’s and age-related dementia.

Anne Trafton | MIT News Office • mit
Nov. 3, 2021 ~6 min

Study shows fragile X treatment can incur resistance, suggests ways around it

While the brain acquires resistance to continuous treatment with mGluR5 inhibitor drugs, lasting effects may still arise if dosing occurs intermittently and during a developmental-critical period.

David Orenstein | Picower Institute for Learning and Memory • mit
Oct. 15, 2021 ~10 min

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