SMART researchers receive grant to develop rapid tests for Covid-19

Using engineered binder proteins to detect viral proteins or antibodies rather than RNA, new tests may overcome current challenges in testing for SARS-CoV-2 virus.

Singapore-MIT Alliance for Research and Technology • mit
May 19, 2020 ~9 min

Tags: singapore-mit-alliance-for-research-and-technology-smart school-of-engineering disease health public-health research rna covid-19 proteins pandemic grants

Biologists build proteins that avoid crosstalk with existing molecules

Engineered signaling pathways could offer a new way to build synthetic biology circuits.

Anne Trafton | MIT News Office • mit
Oct. 23, 2019 ~7 min

Tags: research biology proteins biological-engineering microbes bacteria school-of-science school-of-engineering national-institutes-of-health-nih

How brain cells pick which connections to keep

Novel study shows protein CPG15 acts as a molecular proxy of experience to mark synapses for stabilization.

David Orenstein | Picower Institute for Learning and Memory • mit
Aug. 6, 2019 ~7 min

Tags: picower-institute brain-and-cognitive-sciences school-of-science neuroscience memory biology research proteins

Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis • mit
July 31, 2019 ~6 min

Tags: whitehead-institute picower-institute school-of-science behavior biology brain-and-cognitive-sciences crispr development disease genetics mental-health national-institutes-of-health-nih pharmaceuticals research proteins drug-development

Translating proteins into music, and back

By turning molecular structures into sounds, researchers gain insight into protein structures and create new variations.

David L. Chandler | MIT News Office • mit
June 26, 2019 ~8 min

Tags: research nanoscience-and-nanotechnology proteins civil-and-environmental-engineering school-of-engineering national-institutes-of-health-nih artificial-intelligence machine-learning music apps arts technology-and-society

Predicting sequence from structure

Researchers have devised a faster, more efficient way to design custom peptides and perturb protein-protein interactions.

Raleigh McElvery | Department of Biology • mit
Feb. 15, 2019 ~7 min

Tags: school-of-science biology biological-engineering cancer computer-modeling data disease drug-delivery health research proteins

Enhanced NMR reveals chemical structures in a fraction of the time

Technique could yield insights into complex proteins involved in Alzheimer’s and other diseases.

Anne Trafton | MIT News Office • mit
Jan. 18, 2019 ~5 min

Tags: research chemistry school-of-science proteins biology magnets imaging plasma-science-and-fusion-center

Researchers decode molecule that gives living tissues their flexibility | MIT News

Study reveals atomic structure of tropoelastin, showing what goes wrong in some diseases.

David L. Chandler | MIT News Office • mit
June 25, 2018 ~8 min

Tags:  research  biomaterials  biology  proteins  chemistry  school-of-engineering  civil-and-environmental-engineering  national-science-foundation-nsf  national-institutes-of-health-nih

Structure of key growth regulator revealed | MIT News

Researchers identify the molecular structure of the GATOR1 protein complex, which regulates growth signals in human cells, using cryo-electron microscopy.

Nicole Davis | Whitehead Institute • mit
March 28, 2018 ~6 min

Tags:  research  biology  proteins  whitehead-institute  school-of-science  national-institutes-of-health-nih  national-science-foundation-nsf  cells

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