New technology enables fast protein synthesis

Automated tabletop machine could accelerate the development of novel drugs to treat cancer and other diseases.

Anne Trafton | MIT News Office • mit
May 28, 2020 ~8 min

Tags: chemistry medicine research drug-development proteins school-of-science national-science-foundation-nsf

SMART researchers receive grant to develop rapid tests for Covid-19

Using engineered binder proteins to detect viral proteins or antibodies rather than RNA, new tests may overcome current challenges in testing for SARS-CoV-2 virus.

Singapore-MIT Alliance for Research and Technology • mit
May 19, 2020 ~9 min

Tags: health public-health covid-19 pandemic rna disease research proteins school-of-engineering grants singapore-mit-alliance-for-research-and-technology-smart


Biologists build proteins that avoid crosstalk with existing molecules

Engineered signaling pathways could offer a new way to build synthetic biology circuits.

Anne Trafton | MIT News Office • mit
Oct. 23, 2019 ~7 min

Tags: bacteria biology microbes research proteins school-of-engineering school-of-science national-institutes-of-health-nih biological-engineering

How brain cells pick which connections to keep

Novel study shows protein CPG15 acts as a molecular proxy of experience to mark synapses for stabilization.

David Orenstein | Picower Institute for Learning and Memory • mit
Aug. 6, 2019 ~7 min

Tags: neuroscience biology memory research proteins school-of-science brain-and-cognitive-sciences picower-institute

Speeding up drug discovery for brain diseases

Whitehead Institute team finds drugs that activate a key brain gene; initial tests in cells and mice show promise for rare, untreatable neurodevelopmental disorder.

Nicole Davis • mit
July 31, 2019 ~6 min

Tags: genetics crispr mental-health development biology pharmaceuticals disease research drug-development behavior proteins school-of-science brain-and-cognitive-sciences national-institutes-of-health-nih whitehead-institute picower-institute

Translating proteins into music, and back

By turning molecular structures into sounds, researchers gain insight into protein structures and create new variations.

David L. Chandler | MIT News Office • mit
June 26, 2019 ~8 min

Tags: machine-learning artificial-intelligence music arts research apps proteins school-of-engineering technology-and-society civil-and-environmental-engineering national-institutes-of-health-nih nanoscience-and-nanotechnology

Predicting sequence from structure

Researchers have devised a faster, more efficient way to design custom peptides and perturb protein-protein interactions.

Raleigh McElvery | Department of Biology • mit
Feb. 15, 2019 ~7 min

Tags: health cancer biology data disease research proteins school-of-science computer-modeling biological-engineering drug-delivery

Enhanced NMR reveals chemical structures in a fraction of the time

Technique could yield insights into complex proteins involved in Alzheimer’s and other diseases.

Anne Trafton | MIT News Office • mit
Jan. 18, 2019 ~5 min

Tags: chemistry imaging biology research proteins school-of-science magnets plasma-science-and-fusion-center

Researchers decode molecule that gives living tissues their flexibility | MIT News

Study reveals atomic structure of tropoelastin, showing what goes wrong in some diseases.

David L. Chandler | MIT News Office • mit
June 25, 2018 ~8 min

Tags:  chemistry  biology  research  proteins  school-of-engineering  national-science-foundation-nsf  biomaterials  civil-and-environmental-engineering  national-institutes-of-health-nih

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