BRCA1_and_BRCA2_mutations_and_absolute_cancer_risk.jpg


Summary

Description
English: BRCA1 and BRCA2 mutations and absolute cancer risk.
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Own work

Author
Mikael Häggström , M.D. Author info
- Reusing images
- Conflicts of interest:
None
Mikael Häggström , M.D.

Source data

Cancer Type General Population Risk Risk for Malignancy 1
BRCA1 BRCA2
Breast 12% 46%-87% 38%-84%
Second primary breast 2% w/in 5 yrs 21.1% w/in 10 yrs; 83% by age 70 10.8% w/in 10 yrs; 62% by age 70
Ovarian 1%-2% 39%-63% 16.5%-27%
Male breast 0.10% 1.20% Up to 8.9%
Prostate 6% through age 69 8.6% by age 65 15% by age 65; 20% lifetime
Pancreatic 0.50% 1%-3% 2%-7%
Melanoma (cutaneous & ocular) 1.60% Elevated risk

Licensing

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BRCA1 and BRCA2 mutations and absolute cancer risk

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20 August 2021

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