BRCA1_and_BRCA2_mutations_and_absolute_cancer_risk.jpg
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Summary
Description BRCA1 and BRCA2 mutations and absolute cancer risk.jpg |
English:
BRCA1 and BRCA2 mutations and absolute cancer risk.
|
Date | |
Source |
Own work
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Author | Mikael Häggström , M.D. |
Source data
Cancer Type | General Population Risk | Risk for Malignancy 1 | ||
---|---|---|---|---|
BRCA1 | BRCA2 | |||
Breast | 12% | 46%-87% | 38%-84% | |
Second primary breast | 2% w/in 5 yrs | 21.1% w/in 10 yrs; 83% by age 70 | 10.8% w/in 10 yrs; 62% by age 70 | |
Ovarian | 1%-2% | 39%-63% | 16.5%-27% | |
Male breast | 0.10% | 1.20% | Up to 8.9% | |
Prostate | 6% through age 69 | 8.6% by age 65 | 15% by age 65; 20% lifetime | |
Pancreatic | 0.50% | 1%-3% | 2%-7% | |
Melanoma (cutaneous & ocular) | 1.60% |
Elevated risk
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Licensing
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