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Summary

Description
English: Various therapeutic strategies for targeting cytokine storm. Different stages of the hyperinflammatory immune response can be targeted for therapeutic purposes, with the final aim of modulating and inhibiting cytokine influx in order to restore immune homeostasis. HMGB, high-mobility group protein 1; DAMP, damage-associated molecular pattern; COX, cyclooxygenase.
Date
Source

Bhaskar S, Sinha A, Banach M, Mittoo S, Weissert R, Kass JS, Rajagopal S, Pai AR and Kutty S (2020) Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper. Front. Immunol. 11:1648.

https://doi.org/10.3389/fimmu.2020.01648
Author Sonu Bhaskar, Akansha Sinha, Maciej Banach, Shikha Mittoo, Robert Weissert, Joseph S. Kass, Santhosh Rajagopal, Anupama R. Pai, and Shelby Kutty

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Various therapeutic strategies for targeting cytokine storm.

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10 July 2020

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